Pathohistological features of foci of traumatic osteomyelitis and some clinical and morphological parallels

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Histologic examination of the structure of traumatic osteomyelitic foci in acute and chronic stages, types of bone tissue lesions was performed in experimental morphologic and clinical biopsy material. Differences in various inflammatory changes rates in patients groups were statistically determined. In chronic stage the osteomyelitic focus showed centrally located necrosis and exudate surrounded by internal, fibrous and osseous membranes of the focus capsule. Lesions of bone tissue were heterogenic and stipulated not only by inflammatory process but the ischemic effect as well: osteonecroses, purulent osteonecroses, complete and incomplete sequesters should be differentiated in the affected bone. The rate of various types of inflammation within the internal membrane of focus capsule was reliably different depending on the term of osteomyelitic process (inflammation of high activity was more common under 1 year) and on the fragments fixation method (inflammation of high activity was more often noted in metallosteosynthesis).

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V. Grigorovsky

Institute of Traumatology and Orthopedics of the Academy of Medical Sciences of Ukraine

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乌克兰, Kiev

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2. Rice. 1. Acute traumatic osteomyelitis of the rat tibia, combined with traumatic infarction of the cortical part of the bone and bone marrow (thick arrow); in the perifocal soft tissues - purulent inflammation (thin arrow). Term 3 days. SW. 25. Here and in other figures stained with hematoxylin and eosin.

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3. Rice. 2. Serous-purulent inflammation in acute traumatic osteomyelitis of the rat tibia. Term 3 days. SW. 80.

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4. Rice. 3. Extensive necrosis of the cortical part of the bone and bone marrow of the fragment (thin arrows); exudative inflammation, demarcation and remodeling (thick arrow). Tibia of the patient. SW. 10.

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5. Rice. 4. Continued sequestration of a necrotic area of compact bone, incomplete sequestration (thick arrow); demarcation zone with granulation tissue in a state of purulent inflammation (thin arrow); on the surfaces of the cortical part of the bone - bone regenerates. Patient's femur. SW. 10.

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6. Rice. 5. Chronic traumatic osteomyelitis with productive inflammation of low activity in interfragmentary fibrous tissue. Patient's femur. SW. eight.

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7. Rice. 6. Purulent inflammation of the granulation tissue of the inner shell of the focus capsule in chronic traumatic osteomyelitis. Patient's femur. SW. 200.

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8. Rice. 7. Productive inflammation of high activity in the inner shell of the focus capsule in chronic traumatic osteomyelitis. Tibia of the patient. SW. 140.

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9. Rice. 8. Productive inflammation of low activity in the fibrous membrane of the focus in chronic traumatic osteomyelitis. Incomplete sequestration (arrow). Patient's femur. SW. 60.

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