Clinical and pathogenetic significance of the microvascular component of bone tissue
- Authors: Agafonova A.A.1, Krupatkin A.I.1, Dorokhin A.I.1
-
Affiliations:
- Priorov National Medical Research Center for Traumatology and Orthopedics
- Issue: Vol 30, No 3 (2023)
- Pages: 357-366
- Section: SCIENTIFIC REVIEWS
- URL: https://journals.rcsi.science/0869-8678/article/view/218174
- DOI: https://doi.org/10.17816/vto466576
- ID: 218174
Cite item
Abstract
Bone tissue’s blood circulation and microcirculation are critical to its metabolic and reparative processes. Without the participation of the bone microcirculatory tissue system, it is difficult to exchange oxygen and carbon dioxide, transport of nutrients, and excrete metabolic products. The regeneration of bone tissue is characterized by the pairing of angiogenesis and osteogenesis, which allows the use of microcirculation indicators as additional criteria for the state of reparative processes. Non-invasive approaches for detecting the state of peripheral circulation and microcirculation, which would enable assessing the dynamics of the vascular factor in bone pathology, including after fractures, are most practical in the clinic.
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##article.viewOnOriginalSite##About the authors
Anastasia A. Agafonova
Priorov National Medical Research Center for Traumatology and Orthopedics
Author for correspondence.
Email: nastyaloseva@yandex.ru
ORCID iD: 0000-0002-4675-4313
SPIN-code: 8341-0713
Post-Graduate Student, Traumatologist-Orthopedist, Ultrasound Diagnostic
Russian Federation, MoscowAlexander I. Krupatkin
Priorov National Medical Research Center for Traumatology and Orthopedics
Email: ale.ale02@yandex.ru
ORCID iD: 0000-0001-5582-5200
SPIN-code: 3671-5540
MD, Dr. Sci. (Med.), Professor, Neurologist
Russian Federation, MoscowAlexander I. Dorokhin
Priorov National Medical Research Center for Traumatology and Orthopedics
Email: a.i.dorokhin@mail.ru
ORCID iD: 0000-0003-3263-0755
SPIN-code: 1306-1729
MD, Dr. Sci. (Med.), Traumatologist-Orthopedist
Russian Federation, MoscowReferences
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