Risk of Depressions after Radiation

Мұқаба

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Тек жазылушылар үшін

Аннотация

The review provides data from a number of authors on the risk of developing psychogenic disorders, mainly depression as the most severe pathology, after accidents at nuclear power plants: Three Mile Island, Chernobyl, Fukushima. At the same time, it is important to develop depression even many years after the accident. The second part of the review provides information on the development of depression in patients with head and neck cancer who received head radiotherapy. The number of pathologies in this group significantly exceeds the indicator of the development of pathologies in patients with other types of cancer. The role of non-coding RNAs in the pathogenesis of radio-induced depression is discussed. They are supposed to be used as targets for specific therapy of depression.

Авторлар туралы

G. Zasukhina

Vavilov Institute of General Genetics, Russian Academy of Science

Хат алмасуға жауапты Автор.
Email: zasukhina@vigg.ru
Russia, Moscow

T. Maximova

Vavilov Institute of General Genetics, Russian Academy of Science

Email: zasukhina@vigg.ru
Russia, Moscow

Әдебиет тізімі

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  2. Мустафин Р.Н., Еникеева Р.Ф., Давыдова Ю.Д., Хуснутдинова Э.С. Роль эпигенетических факторов в развитии депрессивных расстройств // Генетика. 2018. Т. 54. № 12. С. 1376–1389. [Mustafin R.N., Enikeeva R.F., Davydova Yu.D., Husnutdinova E.S. Rol’ epigeneticheskih faktorov v razvitii depressivnyh rasstrojstv // Genetika. 2018. V. 54. № 12. P. 1376–1389 (In Russ.)]
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  9. Wang H., Ma Z., Shen H., Wu Z. et al. Early Life Irradiation-induced Hypoplasia and Impairment of Neurogenesis in the Dentate Gyrus and Adult Depression are Mediated by MicroRNA-34a-5p T-cell Intracytoplasmic Antigen-1 Pathway // Cells. 2021. V. 10. P. 2476.
  10. Sen Yang, Zhan Fu, Yan Zhang, Bao Fu, Li Dong. Rs7853346 Polymorphism in lncRNA-PTEN1 and rs 1799864 Polimorphism in CCR2 are Associated with Radiotherapy -induced Cjgnitive Impairment in Subjects with Glioma via Regulating PTENP1-miR19b-CCR2 Signaling Pathway // Biochem. Genet. 2022. V. 60. P. 1159–1176.
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© Г.Д. Засухина, Т.Н. Максимова, 2023

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