TO OPTIMIZATION OF THE TREATMENT OF CHRONIC URETHRITIS CAUSED BY SEXUALLY TRANSMITTED INFECTIONS

The epidemiological features of individual pathogens of sexually transmitted infections, which cause urogenital tract inflammatory diseases, their susceptibility to antibacterial drugs, and β-lactamase activity were studied. Gonorrhea was ascertained to run as an associated infection in 68% of cases with the predominance of microbial associations with Staphylococcus aureus (52%) in the epidemiological structure. There was a substantial rise in the proportion of Neisseria gonorrheae and S. aureus strains producing β-lactamase (95.8 and 93%, respectively). There was a high antibiotic resistance of S. aureus and Escherichia coli strains in association with gonococcus, an increase in the resistance of Ureaplasma urealiticum, Mycoplasma hominis, and M genitalium strains isolated in mixed infections (by 1.25-5.8 times), and a decrease in gonococcal antibiotic susceptibility (by 4 times) in mixed infections. The findings substantiate it necessary to examine for concurrent microflora simultaneously with the identification of a pathogen and the regular monitoring of antibiotic susceptibility in all the isolated pathogens of mono and mixed infections.

Neisseria gonorrheae, Staphylococcus aureus, Neisseria gonorrheae, Staphylococcus aureus, mixed infection, antibiotic resistance