Regulatory and legal regulation of medical care in the «cosmetology» profile in the Russian Federation
- Authors: Kubanov A.A.1, Kolsanova O.A.2, Chertukhina O.B.3
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Affiliations:
- State Scientific Center of Dermatovenerology and Cosmetology
- Clinica New Life
- Samara State Medical University
- Issue: Vol 28, No 5 (2022)
- Pages: 395-407
- Section: Reviews
- URL: https://journals.rcsi.science/0869-2106/article/view/107006
- DOI: https://doi.org/10.17816/medjrf107006
- ID: 107006
Cite item
Abstract
The theoretical and methodological bases of the present study are scientific works, theoretical and methodological developments, current publications of domestic scientists, official normative legal acts, and description of their application in the practical activities of medical organizations providing cosmetology services. This study aimed to examine studies that have focused on the most pressing issues of the legal regulation of medical care to the population of the Russian Federation in the field of «cosmetology», identify the main problems associated with the legal regulation of the industry, and summarize the proposals of medical organizations for its improvement.
In the study, a survey study was conducted, which allowed researchers to identify and summarize the known literature on this topic, regardless of the publication type and study design. The study presents an analysis of the regulatory and legal regulations of the activities of employees and medical organizations providing services in the field of cosmetology. After completing the initial literature search, the authors analyzed, compared, summarized, and systematized the published information.
The analysis made it possible to distribute the data obtained in several key areas of regulatory and legal regulation of domestic cosmetology, i.e., an excursion into history, regulatory and legal support for the activities of a cosmetology medical organization at the present stage, modern requirements for the activities of a doctor, in relation to medical cosmetology care. A content analysis was conducted on the use by medical organizations in the regions of the Russian Federation of the regulatory framework of the cosmetology industry, assessed its effect on the system of providing cosmetological care to the population at the present stage, identified several problems related to the legal regulation of the activities of medical cosmetology organizations and summarized proposals for its improvement.
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##article.viewOnOriginalSite##About the authors
Alexey A. Kubanov
State Scientific Center of Dermatovenerology and Cosmetology
Email: alex@cnikvi.ru
ORCID iD: 0000-0002-7625-0503
SPIN-code: 8771-4990
Dr. Sci. (Med.), professor
Russian Federation, MoscowOlga A. Kolsanova
Clinica New Life
Email: kosmetologso@mail.ru
ORCID iD: 0000-0002-0301-6310
SPIN-code: 6128-3388
MD, Cand. Sci. (Med.)
Russian Federation, SamaraOlga B. Chertukhina
Samara State Medical University
Author for correspondence.
Email: o.b.chertukhina@samsmu.ru
ORCID iD: 0000-0003-2230-7292
SPIN-code: 1962-4682
Dr. Sci. (Med.), professor
Russian Federation, SamaraReferences
- Alieva AM, Reznik EV, Hasanova ET, et al. Clinical value of blood biomarkers in patients with chronic heart failure. The Russian Archives of Internal Medicine. 2018;8(5):333–345. (In Russ). doi: 10.20514 / 2226-6704-2018-8-5-333-345
- Alieva AM, Pinchuk TV, Almazova II, et al. Сlinical value of blood biomarker ST2 in patients with chronic heart failure. Consilium Medicum. 2021;23(6):522–526. (In Russ). doi: 10.26442/20751753.2021.6.200606
- Alieva AM, Baykova IE, Kislyakov VA. Galectin-3: diagnostic and prognostic value in patients with chronic heart failure. Therapevti cheskii arkhiv. 2019;91(9):145–149. (In Russ). doi: 10.26442/00403660.2019.09.000226
- Alieva AM, Almazova II, Pinchuk TV. Fractalkin and cardiovascular diseases. Consilium Medicum. 2020;22(5):83–86. (In Russ). doi: 10.26442/20751753.2020.5.200186
- Kuro-o M, Matsumura Y, Aizawa H, et al. Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature. 1997;390(6655):45–51. doi: 10.1038/36285
- Timoshchenko OV, Nikitin YuP. Klotho protein and atherosclerosis. Ateroscleroz. 2017;13(4):38–41. (In Russ). doi: 10.15372/ATER20170406
- Masuda H, Chikuda H, Suga T, et al. Regulation of multiple ageing-like phenotypes by inducible klotho gene expression in klotho mutant mice. Mech Ageing Dev. 2005;126(12):1274–1283. doi: 10.1016/j.mad.2005.07.007
- Bi X, Yang K, Zhang B, Zhao J. The protective role of Klotho in CKD-associated cardiovascular disease. Kidney Dis. 2020;6(6):395–406. doi: 10.1159/000509369
- Matsumura Y, Aizawa H, Shiraki-Iida T, et al. Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein. Biochem Biophys Res Commun. 1998;242(3):626–630. doi: 10.1006/bbrc.1997.8019
- Bloch L, Sineshchekova O, Reichenbach D, et al. Klotho is a substrate for alpha-, beta- and gamma-secretase. FEBS Lett. 2009;583(19):3221–3224. doi: 10.1016/j.febslet.2009.09.009
- Veronesi F, Borsari V, Cherubini A, Fini M. Association of Klotho with physical performance and frailty in middle-aged and older adults: a systematic review. Exp Gerontol. 2021;154:111518. doi: 10.1016/j.exger.2021.111518
- Tomo S, Birdi A, Yadav D, et al. Klotho: a possible role in the pathophysiology of nephrotic syndrome. EJIFCC. 2022;33(1):3–10.
- Van Husen M, Fischer AK, Lehnhardt A, et al. Fibroblast growth factor 23 and bone metabolism in children with chronic kidney disease. Kidney Int. 2010;78(2):200–206. doi: 10.1038/ ki.2010.107
- Andrukhova O, Smorodchenko A, Egerbacher M, et al. FGF23 promotes renal calcium reabsorption through the TRPV5 channel. EMBO J. 2014;33(3):229–246. doi: 10.1002/embj.201284188
- Yamazaki Y, Imura A, Urakawa I, et al. Establishment of sandwich ELISA for soluble alpha-Klotho measurement: age-dependent change of soluble alpha-Klotho levels in healthy subjects. Biochem Biophys Res Commun. 2010;398(3):513–518. doi: 10.1016/j.bbrc.2010.06.110.
- Pedersen L, Pedersen SM, Brasen CL, Rasmussen LM. Soluble serum Klotho levels in healthy subjects. Comparison of two different immunoassays. Clin Biochem. 2013;46(12):1079–1083. doi: 10.1016/j.clinbiochem.2013.05.046
- Tyurenkov IN, Perfilova VN, Nesterova AA, Glinka Y. Klotho protein and cardio-vascular system. Biochemistry (Moscow). 2021;86(2):158–174. (In Russ). doi: 10.31857/S0320972521020020
- Kim J, Hwang K, Park K, et al. Biological role of anti-aging pro tein Klotho. J Lifestyle Med. 2015;5(1):1–6. doi: 10.15280/jlm.2015.5.1.1
- Dalton GD, Xie J, An S, Huang C. New Insights into the Mechanism of Action of Soluble Klotho. Front Endocrinol (Lausanne). 2017; 8:323. doi: 10.3389/fendo.2017.00323
- Doi S, Zou Y, Togao O, et al. Klotho inhibits transforming growth factor-β1 (TGF-β1) signaling and suppresses renal fibrosis and cancer metastasis in mice. J Biol Chem. 2011;286(10):8655–8665. doi: 10.1074/jbc.M110.174037
- Olejnik A, Franczak A, Krzywonos-Zawadzka A, et al. The biological role of Klotho protein in the development of cardiovascular diseases. Biomed Res Int. 2018;5171945. doi: 10.1155/2018/5171945
- Morshneva AV. FoxO transcription factors as multifunctional cell regulators. Tsitologiya. 2020;62(10):687–698. (In Russ). doi: 10.31857/S0041377120100041
- Cui W, Leng B, Wang G. Klotho protein inhibits H2O2-induced oxidative injury in endothelial cells via regulation of PI3K/AKT/Nrf2/HO-1 pathways. Can J Physiol Pharmacol. 2019;97(5):370–376. doi: 10.1139/cjpp-2018-0277
- Yao Y, Wang Y, Zhang Y, Liu C. Klotho ameliorates oxidized low-density lipoprotein (ox-LDL)-induced oxidative stress via re gulating LOX-1 and PI3K/Akt/eNOS pathways. Lipids Health Dis. 2017;16(1):77. doi: 10.1186/s12944-017-0447-0
- Takenaka T, Kobori H, Miyazaki T, et al. Klotho protein supplementation reduces blood pressure and renal hypertrophy in db/db mice, a model of type 2 diabetes. Acta Physiol (Oxf). 2019;225(2):e13190. doi: 10.1111/apha.13190
- Lim SW, Jin L, Luo K, et al. Klotho enhances FoxO3-mediated manganese superoxide dismutase expression by negatively regulating PI3K/AKT pathway during tacrolimus-induced oxidative stress. Cell Death Dis. 2017;8(8): e2972. doi: 10.1038/cddis.2017.365
- Yamamoto M, Clark JD, Pastor JV, et al. Regulation of oxi dative stress by the anti-aging hormone klotho. J Biol Chem. 2005;280(45):38029–38034. doi: 10.1074/jbc.m509039200
- Thurston RD, Larmonier CB, Majewski PM, et al. Downregulation of aging-related Klotho gene in experimental colitis: the role of TNF and IFN-γ Gastroenterology. 2010;138(4):1384–1394.e2. doi: 10.1053/j.gastro.2009.12.002
- Mitobe M, Yoshida T, Sugiura H, et al. Oxidative stress decreases klotho expression in a mouse kidney cell line. Nephron Exp Nephrol. 2005;101(2):e67–e74. doi: 10.1159/000086500
- Oh HJ, Nam BY, Lee MJ, et al. Decreased circulating klotho levels in patients undergoing dialysis and relationship to oxidative stress and inflammation. Perit Dial Int. 2015;35(1):43–51. doi: 10.3747/pdi.2013.00150
- Kusaba T, Okigaki M, Matui A, et al. Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity. Proc Natl Acad Sci USA. 2010;107(45):19308–19313. doi: 10.1073/pnas.1008544107
- Semba RD, Cappola AR, Sun K, et al. Plasma klotho and cardiovascular disease in adults. J Am Geriatr Soc. 2011;59(9):1596–1601. doi: 10.1111/j.1532-5415.2011.03558.x
- Kokkinaki M, Abu-Asab M, Gunawardena N, et al. Klotho regulates retinal pigment epithelial functions and protects against oxidative stress. J Neurosci. 2013;33(41):16346–16359. doi: 10.1523/JNEUROSCI.0402-13.2013
- Zhao Y, Meng C, Wang Y, et al. IL-1β inhibits β-Klotho expression and FGF19 signaling in hepatocytes. Am J Physiol Endocrinol Metab. 2016;310(4):E289–300. doi: 10.1152/ajpendo.00356.2015
- Graham SE, Clarke SL, Wu KH, et al. The power of genetic diversity in genome-wide association studies of lipids. Nature. 2021;600(7890):675–679. doi: 10.1038/s41586-021-04064-3
- Arking DE, Becker DM, Yanek LR, et al. KLOTHO allele status and the risk of early-onset occult coronary artery disease. Am J Hum Genet. 2003;72(5):1154–1161. doi: 10.1086/375035
- Majumdar V, Nagaraja D, Christopher R. Association of the functional KL-VS variant of Klotho gene with early-onset ischemic stroke. Biochem Biophys Res Commun. 2010;403(3-4):412–416. doi: 10.1016/j.bbrc.2010.11.045
- Oguro R, Kamide K, Kokubo Y, et al. Association of carotid atherosclerosis with genetic polymorphisms of the klotho gene in patients with hypertension. Geriatr Gerontol Int. 2010;10(4):311–318. doi: 10.1111/j.1447-0594.2010.00612
- Imamura A, Okumura K, Ogawa Y, et al. Klotho gene polymorphism may be a genetic risk factor for atherosclerotic coronary artery disease but not for vasospastic angina in Japanese. Clin Chim Acta. 2006;371(1-2):66–70. doi: 10.1016/j.cca.2006.02.021
- Telci D, Dogan AU, Ozbek E, et al. KLOTHO gene polymorphism of G395A is associated with kidney stones. Am J Nephrol. 2011;33(4):337–343. doi: 10.1159/000325505
- Kawano KI, Ogata N, Chiano M, et al. Klotho gene polymorphisms associated with bone density of aged postmenopausal women. J Bone Miner Res. 2002;17(10):1744–1751. doi: 10.1359/jbmr.2002.17.10.1744
- Majumdar V, Jose D, Christopher R. Influence of Klotho genotypes on plasma NO(x) levels in South Indian population. Thromb Res. 2011;128(3):251–255. doi: 10.1016/j.thromres.2011.04.002
- Pavlatou MG, Remaley AT, Gold PW. Klotho: a humeral mediator in CSF and plasma that influences longevity and susceptibility to multiple complex disorders, including depression. Transl Psychiatry. 2016;6(8):e876. doi: 10.1038/tp.2016.135
- Rhee EJ, Oh KW, Yun EJ, et al. Relationship between polymorphisms G395A in promoter and C1818T in exon 4 of the KLOTHO gene with glucose metabolism and cardiovascular risk factors in Korean women. J Endocrinol Invest. 2006;29(7):613–618. doi: 10.1007/BF03344160
- Elghoroury EA, Fadel FI, Elshamaa MF, et al. Klotho G-395A gene polymorphism: impact on progression of end-stage renal disease and development of cardiovascular complications in children on dialysis. Pediatr Nephrol. 2018;33(6):1–9. doi: 10.1007/s00467-017-3877-z
- Valdivielso JM, Bozic M, Galimudi RK, et al. Association of the rs495392 Klotho polymorphism with atheromatosis progression in patients with chronic kidney disease. Nephrol Dial Transplant. 2019;34(12):2079–2088. doi: 10.1093/ndt/gfy207
- Keles N, Caliskan M, Dogan B, et al. Is low serum Klotho level associated with alterations in coronary flow reserve? Echocardio graphy. 2016;33(6):881–888. doi: 10.1111/echo.13176
- Kresovich JK, Bulka CM. Low serum Klotho associated with all-cause mortality among a nationally representative sample of Ameri can adults. J Gerontol A Biol Sci Med Sci. 2022;77(3):452–456. doi: 10.1093/gerona/glab308
- Martin-Nunez E, Donate-Correa J, Lopez-Castillo A, et al. Soluble levels and endogenous vascular gene expression of KLOTHO are related to inflammation in human atherosclerotic disease. Clin Sci (Lond). 2017;131(21):2601–2609. doi: 10.1042/CS20171242
- Keles N, Caliskan M, Dogan B, et al. Low serum level of Klotho is an early predictor of atherosclerosis. Tohoku J Exp Med. 2015;237(1):17–23. doi: 10.1620/tjem.237.17
- Kazemi Fard T, Ahmadi R, Akbari T, et al. Klotho, FOXO1 and cytokines associations in patients with coronary artery disease. Cytokine. 2021;141:155443. doi: 10.1016/j.cyto.2021.155443
- Corsetti G, Pasini E, Scarabelli TM, et al. Decreased expression of Klotho in cardiac atria biopsy samples from patients at higher risk of atherosclerotic cardiovascular disease. J Geriatr Cardiol. 2016;13(8):701–711. doi: 10.11909/j.issn.1671-5411.2016.08.009
- Wei N, Zhang R, Zhu Z, et al. Adropin and Irisin deficiencies are associated with presence of diagonal earlobe crease in CAD pa tients. Front Cardiovasc Med. 2021;8:719763. doi: 10.3389/fcvm.2021.719763
- Wang J, Zhu ZF, Liu FQ, et al. Patients with earlobe crease may associate with lower concentration of the age-suppressing hormone Klotho. Int J Gen Med. 2021;14:8797–8803. doi: 10.2147/IJGM.S300309
- Martin-Nunez E, Perez-Castro A, Tagua VG, et al. Klotho expression in peripheral blood circulating cells is associated with vascular and systemic inflammation in atherosclerotic vascular disease. Sci Rep. 2022;12(1):8422. doi: 10.1038/s41598-022-12548-z
- Liu W, Chen X, Wu M, et al. Recombinant Klotho protein enhances cholesterol efflux of THP-1 macrophage-derived foam cells via suppressing Wnt/β-catenin signaling pathway. BMC Cardiovasc Disord. 2020;20(1):120. doi: 10.1186/s12872-020-01400-9
- Sun X, Chen L, He Y, Zheng L. Circulating α-Klotho levels in relation to cardiovascular diseases: a mendelian randomization study. Front Endocrinol (Lausanne). 2022;13:842846. doi: 10.3389/fendo.2022.842846
- Navarro-Gonzalez JF, Donate-Correa J, Muros de Fuentes M, et al. Reduced Klotho is associated with the presence and severity of coronary artery disease. Heart. 2014;100(1):34–40. doi: 10.1136/heartjnl-2013-304746
- Gocer K, Aykan AC, Kilinc M, Gocer NS. Association of serum FGF-23, klotho, fetuin-A, osteopontin, osteoprotegerin and hs-CRP levels with coronary artery disease. Scand J Clin Lab Invest. 2020;80(4):277–281. doi: 10.1080/00365513.2020.1728786
- Bergmark BA, Udell JA, Morrow DA, et al. Klotho, fibroblast growth factor-23, and the renin-angiotensin system — an analysis from the PEACE trial. Eur J Heart Fail. 2019;21(4):462–470. doi: 10.1002/ejhf.1424
- Xu JP, Zeng RX, He MH, et al. Associations between serum soluble α-Klotho and the prevalence of specific cardiovascular disease. Front Cardiovasc Med. 2022;9:899307. doi: 10.3389/fcvm.2022.899307
- Koga S, Ikeda S, Akashi R, et al. Serum soluble Klotho is inversely related to coronary artery calcification assessed by intravascular ultrasound in patients with stable coronary artery disease. J Cardiol. 2021;77(6):583–589. doi: 10.1016/j.jjcc.2020.11.014
- Abdallah E, Mosbah O, Khalifa G, et al. Assessment of the relationship between serum soluble Klotho and carotid intima-media thickness and left ventricular dysfunction in hemodialysis patients. Kidney Res Clin Pract. 2016;35(1):42–49. doi: 10.1016/j.krcp.2015.12.006
- Kespleri EV, Polunina OS, Аkhmineeva AKh, et al. Analysis of Klotho protein level in patients with myocardial infarction and concurrent chronic obstructive pulmonary disease with different ma nifestations. Tuberculosis and Lung Diseases. 2021;99(8):27–32. (In Russ). doi: 10.21292/2075-1230-2021-99-8-27-32
- Orces C.H. The association between serum soluble klotho levels and abdominal aorta calcification in older adults. Aging Clin Exp Res. 2022;34(6):1447–1452. doi: 10.1007/s40520-021-02053-0
- Zhou X, Li S, Wang Z, et al. Klotho protein: а potential therapeutic agent during myocardial ischemia and reperfusion. Int J Cardiol. 2015;191:227–228. doi: 10.1016/j.ijcard.2015.05.029
- Olejnik A, Krzywonos-Zawadzka A, Banaszkiewicz M, Bil-Lula I. Klotho protein contributes to cardioprotection during ischaemia/reperfusion injury. J Cell Mol Med. 2020;24(11):6448–6458. doi: 10.1111/jcmm.15293
- Olejnik A, Banaszkiewicz M, Krzywonos-Zawadzka A, Bil-Lula I. The Klotho protein supports redox balance and metabolic functions of cardiomyocytes during ischemia/reperfusion injury. Cardiol J. 2021. doi: 10.5603/CJ. a2021.0174
- Myung J, Beom JH, Kim JH, et al. Recombinant Klotho protein ameliorates myocardial ischemia/reperfusion injury by attenuating sterile inflammation. Biomedicines. 2022;10(4):894. doi: 10.3390/biomedicines10040894
- Qiu X, Guo Q, Xiong W, et al. Therapeutic effect of astragaloside-IV on bradycardia is involved in up-regulating klotho expression. Life Sci. 2016;144:94–102. doi: 10.1016/j.lfs.2015.11.021
- Cheng L, Zhang L, Yang J, Hao L. Activation of peroxisome proliferator-activated receptor γ inhibits vascular calcification by upre gulating Klotho. Exp Ther Med. 2017;13(2):467–474. doi: 10.3892/etm.2016.3996
- Narumiya H, Sasaki S, Kuwahara N, et al. HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells. Cardiovasc Res. 2004;64(2):331–336. doi: 10.1016/j.cardiores.2004.07.011
- Youssef OM, Morsy AI, El-Shahat MA, et al. The neuroprotective effect of simvastatin on the cerebellum of experimentally-induced diabetic rats through klotho upregulation: аn immunohistochemical study. J Chem Neuroanat. 2020;108:101803. doi: 10.1016/j.jchemneu.2020.101803
- Maquigussa E, Paterno JC, de Oliveira Pokorny GH, et al. Klotho and PPAR gamma activation mediate the renoprotective effect of Losartan in the 5/6 nephrectomy model. Front Physiol. 2018;9:1033. doi: 10.3389/fphys.2018.01033
- Yoon HE, Ghee JY, Piao S, et al. Angiotensin II blockade upregu lates the expression of Klotho, the anti-ageing gene, in an experi mental model of chronic cyclosporine nephropathy. Nephrol Dial Transplant. 2011;26(3):800–813. doi: 10.1093/ndt/gfq537
- Haussler MR, Whitfield GK, Haussler CA, et al. 1,25-Dihydroxyvitamin D and Klotho: a tale of two renal hormones coming of age. Vitam Horm. 2016;100:165–230. doi: 10.1016/bs.vh.2015.11.005
- Pavlov S, Nikitchenko Y, Tykhonovska М. The impact of the chemical agents of different pharmacological groups on the klotho protein concentration in the cardiomyocyte and neurocyte suspension in 120-minute hypoxia in vitro. Georgian Med News. 2020;(306): 184–188