Successful Management of Nasal Cavity and Paranasal Sinus Neuroendocrine Carcinoma with Upper Airway Obstruction During Pregnancy: A Case Report

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Introduction. Sinonasal neuroendocrine carcinoma is a rare neoplasm with an incidence of 0.2–0.8 %, characterized by an aggressive clinical course. Theco-occurrence of this malignancy with pregnancy has been reported only in isolated clinical cases to date. Case Description. We present a case of stage IV (cT4aN3M0) neuroendocrine carcinoma of the ethmoid bone in a 26-year-old pregnant patient who achieved a complete objective response following EP chemotherapy. Conclusion. The management of malignant neoplasms during pregnancy represents a significant challenge in contemporary oncology, particularly given the increasing incidence of cancer diagnoses during gestation, including rare morphological subtypes.

Sobre autores

A. Konova

Almazov National Medical Research Centre

Email: konovaamix@gmail.com
ORCID ID: 0009-0004-7104-8447
Código SPIN: 6768-5550
St. Petersburg, the Russian Federation

E. Zorina

Almazov National Medical Research Centre

Email: konovaamix@gmail.com
ORCID ID: 0000-0002-5928-9625
Código SPIN: 3132-7676
St. Petersburg, the Russian Federation

S. Sklyar

Polenov Neurosurgical Institute — a branch of the Almazov National Medical Research Centre

Email: konovaamix@gmail.com
ORCID ID: 0000-0002-3284-9688
Código SPIN: 4679-3548
St. Petersburg, the Russian Federation

I. Danilov

Almazov National Medical Research Centre

Email: konovaamix@gmail.com
ORCID ID: 0000-0001-9540-7812
Código SPIN: 3267-5056
St. Petersburg, the Russian Federation

E. Ulrikh

N.N. Petrov National Medicine Research Center of Oncology; Almazov National Medical Research Centre

Email: konovaamix@gmail.com
ORCID ID: 0000-0002-2701-8812
Código SPIN: 1110-1844
St. Petersburg, the Russian Federation; St. Petersburg

Bibliografia

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