Effect of Total Duration and Amount of Performed Space Flights on the Human Plasma Hemostasis System
- Авторы: Kuzichkin D.1, Markin A.1, Juravlyova O.1, Krivitsyna Z.1, Vostrikova L.1, Zabolotskaya I.1, Loginov V.1
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Учреждения:
- Institute of Biomedical Problems, Russian Academy of Sciences
- Выпуск: Том 45, № 6 (2019)
- Страницы: 701-704
- Раздел: Short Communications
- URL: https://journals.rcsi.science/0362-1197/article/view/178398
- DOI: https://doi.org/10.1134/S0362119719050074
- ID: 178398
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Аннотация
This study involved 27 cosmonauts aged from 37 to 59 years. First, we carried out a correlation analysis of hemostatic parameters and the total duration of space flights. No statistically significant correlation was found for any parameters at any terms of the survey. Then, the sample of cosmonauts was divided into three groups according to the amount of performed flights. We studied the dynamics of parameters within the groups and observed an increase in the coagulation contact phase potential in the dynamics of post-flight studies on the basis of the shortened activated partial thromboplastin time with a tendency of this parameter to restore to the baseline level. This tendency was weakening after three space flights. The observed changes appear to be due to the cumulative effect of space flight factors and the stress of readaptation to terrestrial conditions.
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Об авторах
D. Kuzichkin
Institute of Biomedical Problems, Russian Academy of Sciences
Email: andre_markine@mail.ru
Россия, Moscow, 123007
A. Markin
Institute of Biomedical Problems, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: andre_markine@mail.ru
Россия, Moscow, 123007
O. Juravlyova
Institute of Biomedical Problems, Russian Academy of Sciences
Email: andre_markine@mail.ru
Россия, Moscow, 123007
Z. Krivitsyna
Institute of Biomedical Problems, Russian Academy of Sciences
Email: andre_markine@mail.ru
Россия, Moscow, 123007
L. Vostrikova
Institute of Biomedical Problems, Russian Academy of Sciences
Email: andre_markine@mail.ru
Россия, Moscow, 123007
I. Zabolotskaya
Institute of Biomedical Problems, Russian Academy of Sciences
Email: andre_markine@mail.ru
Россия, Moscow, 123007
V. Loginov
Institute of Biomedical Problems, Russian Academy of Sciences
Email: andre_markine@mail.ru
Россия, Moscow, 123007