PET-CT in Early Detection of Alzheimer’s Disease: A Case Report
- Authors: Prokopenko S.V.1, Savel’eva A.A.2, Belugin K.V.2, Badrin E.A.2, Ozerskaya A.V.2, Karlova E.A.2, Tokarev N.A.2, Chanchikova N.G.2, Koryagina T.D.1, Bezdenezhnykh A.F.1, Mozheyko E.Y.1, Mar’ina N.M.2, Barankin B.V.2, Shepelevich N.V.2
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Affiliations:
- Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky
- Federal Siberian Research Clinical Center
- Issue: Vol 44, No 8 (2018)
- Pages: 864-868
- Section: Article
- URL: https://journals.rcsi.science/0362-1197/article/view/177978
- DOI: https://doi.org/10.1134/S0362119718080108
- ID: 177978
Cite item
Abstract
The article describes a clinical case of a female patient with Alzheimer’s disease at an early stage of the neurodegenerative process. The patient did not have any complaints. She was taken to the neuropsychologist by her husband who was concerned by the patient’s family history (his mother-in-law suffered from Alzheimer’s disease) and some memory problems that his wife had recently encountered. The diagnosis was suspected based on the results of neuropsychological evaluation of cognitive functions corresponding to mild cognitive impairment. To confirm the presence of a neurodegenerative disease, brain positron-emission tomography with F-18 fluorodesoxyglucose (FDG) was performed. Hypometabolism of the radio-tracer was detected in the cortex of temporal and parietal lobes, in the association cortex of the left temporal and the right occipital lobes, and in the posterior part of the left cyngulate gyrus. These findings correlated with the patient’s cognitive evaluation and thus provided the nosological diagnosis at an early stage of the disease.
About the authors
S. V. Prokopenko
Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk, 660049
A. A. Savel’eva
Federal Siberian Research Clinical Center
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk
K. V. Belugin
Federal Siberian Research Clinical Center
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk
E. A. Badrin
Federal Siberian Research Clinical Center
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk
A. V. Ozerskaya
Federal Siberian Research Clinical Center
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk
E. A. Karlova
Federal Siberian Research Clinical Center
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk
N. A. Tokarev
Federal Siberian Research Clinical Center
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk
N. G. Chanchikova
Federal Siberian Research Clinical Center
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk
T. D. Koryagina
Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky
Author for correspondence.
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk, 660049
A. F. Bezdenezhnykh
Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk, 660049
E. Yu. Mozheyko
Krasnoyarsk State Medical University named after Prof. V.F. Voyno-Yasenetsky
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk, 660049
N. M. Mar’ina
Federal Siberian Research Clinical Center
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk
B. V. Barankin
Federal Siberian Research Clinical Center
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk
N. V. Shepelevich
Federal Siberian Research Clinical Center
Email: t6868@mail.ru
Russian Federation, Krasnoyarsk