Optimization of the Production Process of Biologically-Active Betulin Diacetate from Raw and Activated Birch Bark


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The effect of the conditions of the acetylation process of raw and activated birch bark on the yield and composition of the products is investigated. The structure of biologically active betulin diacetate (BDA) is confirmed with physicochemical methods. The optimal regimes of the one-step original method for the production of BDA from raw and activated birch bark are established using the experimental and computational techniques.

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S. Kuznetsova

Institute of Chemistry and Chemical Technology SB RAS; Siberian Federal University

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Email: ksa@icct.ru
俄罗斯联邦, Krasnoyarsk, 660036; Krasnoyarsk, 660041

B. Kuznetsov

Institute of Chemistry and Chemical Technology SB RAS; Siberian Federal University

Email: ksa@icct.ru
俄罗斯联邦, Krasnoyarsk, 660036; Krasnoyarsk, 660041

Yu. Malyar

Institute of Chemistry and Chemical Technology SB RAS; Siberian Federal University

Email: ksa@icct.ru
俄罗斯联邦, Krasnoyarsk, 660036; Krasnoyarsk, 660041

E. Skurydina

Institute of Chemistry and Chemical Technology SB RAS

Email: ksa@icct.ru
俄罗斯联邦, Krasnoyarsk, 660036

G. Skvortsova

Institute of Chemistry and Chemical Technology SB RAS

Email: ksa@icct.ru
俄罗斯联邦, Krasnoyarsk, 660036

R. Pen

Reshetnev Siberian State University of Science and Technology

Email: ksa@icct.ru
俄罗斯联邦, Krasnoyarsk, 660037

N. Chesnokov

Institute of Chemistry and Chemical Technology SB RAS; Siberian Federal University

Email: ksa@icct.ru
俄罗斯联邦, Krasnoyarsk, 660036; Krasnoyarsk, 660041

O. Khanchich

Moscow Technological Institute

Email: ksa@icct.ru
俄罗斯联邦, Moscow, 119334

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