Pharmacological and clinical feature of rebamipide: new therapeutic targets
- 作者: Zvyaglova M.1, Knyazev O.1, Parfenov A.1
-
隶属关系:
- Loginov Moscow Clinical Research Center
- 期: 卷 92, 编号 2 (2020)
- 页面: 104-111
- 栏目: Original articles
- URL: https://journals.rcsi.science/0040-3660/article/view/33918
- DOI: https://doi.org/10.26442/00403660.2020.02.000569
- ID: 33918
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Rebamipide is a cytoprotector developed in Japan where it has been successfully used for the treatment of stomach diseases for 30 years. Initially discovered effects of the drug included the induction of prostaglandins and the elimination of free oxygen radicals. Recent studies discovered new therapeutic targets of the drug, its new forms that made possible using rebamipid for the treatment of such diseases as NSAID enteropathy, ulcerative colitis, radiation colitis, pouchitis, enteropathy with impaired membrane digestion. It is used in endoscopy, ophthalmology, chemotherapy, rheumatology. The aim of this review is to present current information about the pharmacological and clinical feature of rebamipide and to study its therapeutic potential.
作者简介
M. Zvyaglova
Loginov Moscow Clinical Research Center
编辑信件的主要联系方式.
Email: asfold@mail.ru
м.н.с. отд-ния воспалительных заболеваний кишечника
俄罗斯联邦, MoscowO. Knyazev
Loginov Moscow Clinical Research Center
Email: asfold@mail.ru
д.м.н., зав. отд-нием воспалительных заболеваний кишечника
俄罗斯联邦, MoscowA. Parfenov
Loginov Moscow Clinical Research Center
Email: asfold@mail.ru
д.м.н., проф., зав. отд. патологии кишечника
俄罗斯联邦, Moscow参考
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