Diagnosis of cryptococcal encephalitis in a patient with mature B-cell lymphoblastic leukemia


如何引用文章

全文:

详细

Fungal meningoencephalitides are one of the most menacing infectious complications in hematologic cancer patients in the presence of myelotoxic agranulocytosis. Due to diagnostic difficulties, mortality in these cases can be as high as 100%. The causative agent of cryptococcosis is Cryptococcus neoformans; damage to the brain arachnoid membranes and substance is diagnosed in 70-90% of cases. Unlike bacterial meningitis, the meningeal symptoms typical of cryptococcal meningoencephalitis are not characteristic.
The paper gives a case of successful treatment for cryptococcal meningoencephalitis in the presence of agranulocytosis, the diagnosis of which is based on the detection of abnormal MR signal foci by magnetic resonance imaging and identification of the cryptococcal antigen - glucuronoxylomannan in spinal fluid.

作者简介

Lev Gotman

ГУ Гематологический научный центр РАМН

д-р мед. наук, отд-ние рентгено-радиологии; ГУ Гематологический научный центр РАМН

Galina Yatsyk

ГУ Гематологический научный центр РАМН

Email: Ytsyk@rambler.ru
врач-рентгенолог, отд-ние рентгено-радиологии; ГУ Гематологический научный центр РАМН

Vladimir Vorob'ev

ГУ Гематологический научный центр РАМН

Email: morela@mail.ru
аспирант; ГУ Гематологический научный центр РАМН

L Gotman

Hematology Research Center

Hematology Research Center

G Yatsyk

Hematology Research Center

Hematology Research Center

V Vorobyev

Hematology Research Center

Hematology Research Center

参考

  1. Аравийский Р. А., Климко Н. А., Васильева Н. В. Диагностика микозов. СПб.: Изд. дом СПиМАПО; 2004. 83-121.
  2. Корниенко В. Н., Пронин И. Н. Диагностическая нефрорадиология. М.; 2006: 1024-1081.
  3. Popovich M., Arthur R., Helmer E. CT of intracranialis cryptococcosis. Am. J. Neuroradiol. 1990; 11: 139-142.
  4. Witerman M. Intracranial infection. In: Atlas W., ed. MRI of the brain and spine. 3rd ed. Philadelphia. Lippincott Williams & Wilkin; 2002: 1099-1175.

版权所有 © Consilium Medicum, 2010

Creative Commons License
此作品已接受知识共享署名-非商业性使用-相同方式共享 4.0国际许可协议的许可。
 
 


##common.cookie##