Clinical value of the time course of changes in postprandial intragastric acidity


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Aim. to study the level and duration of postprandial pH abnormalities in the body of the stomach in healthy individuals and in patients with duodenal peptic ulcer (DPU).
Subjects and methods. 24-hour pH-metry was used to study the degree and duration of postprandial pH abnormalities in the body of the stomach in 50 healthy individuals and 188 patients with DPU.
Results. Interdigestive gastric pH in healthy individuals was significantly higher than that in patients with DPU; food intake was followed by an 86 ± 3.4% increase in pH, the latter returned to the baseline pH values within 64.7-70.3 minutes. In the uncomplicated course of DPU, the mean postprandial pH increase was comparable in the level and duration with the similar indices in healthy individuals. Complicated DPU was characterized by a short-term and insignificant increase in postprandial pH.
Conclusion. The mean postprandial pH increase and the time of its return to the baseline level in uncomplicated DPU were comparable with those in healthy individuals; there was a significant reduction in these indices in complicated DPU.

作者简介

Irina Kolesnikova

ГОУ ВПО Тверская государственная медицинская академия

Email: famco@tvcom.ru
кафедра госпитальной терапиид-р мед. наук, доц; ГОУ ВПО Тверская государственная медицинская академия

I Kolesnikova

参考

  1. Покровский А. А., Самсонов М. А. (ред.) Справочник по диетологии. М.: Медицина; 1981.
  2. Barlow A. P., Hinder R. A., DeMester T. R., Fuchs K. Twenty-four-hour gastric luminal pH in normal subjects: influence of probe position, food, posture, and duodenogastric reflux. Am. J. Gastroenterol. 1995; 90(7): 1186-1187.
  3. Охлобыстин А. В. Современные возможности применения антацидных препаратов. Рус. мед. журн. Бол. органов пищевар. 2002; 2(4): 51-54.
  4. Горшков В. А., Авалуева Е. Б., Шабалина М. О. Питание и кислотно-протеолитическая агрессия в желудке при дуоденальной язве. Рос. журн. гастроэнтерол., гепатол., колопроктол. 2000; 1: 29-38.
  5. Маев И. В., Вьючнова Е. С., Лебедева Е. Г. Как поставить диагноз функциональной (неязвенной) диспепсии (обзор)? Тер. арх. 2004; 76(11): 57-60.

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