Potentialities of high-resolution computed tomography in diagnosis of pulmonary lesions after bone marrow transplantation in blood diseases
- 作者: Gotman L1, Kostina I1, Vishnevskaya E1, Togonidze D1, Mendeleeva L1, Lyubimova L1, Savchenko V1
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隶属关系:
- ГНЦ РАМН
- 期: 卷 79, 编号 4 (2004)
- 页面: 45-50
- 栏目: Editorial
- URL: https://journals.rcsi.science/0040-3660/article/view/29819
- ID: 29819
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Results. Twenty four patients were examined before BMT. Of them, 18 patients had roentgenomorphological changes of the parenchyma, primarily, diffuse. Three patients were examined during conditioning, two cases had signs of toxic pulmonitis. One day after allo-BMT all the patients exhibited lowering of densitometric values of pulmonary tissue by 70 HU vs the baseline. Infectious affection of the lungs was diagnosed in 13 cases during day 0-100. From day 100 after allo-BMT 7 recipients were observed. In 6 cases the changes resulted from transplant against host reaction. Infectious affection of pulmonary tissue was observed in 1 case. Characteristic x-ray picture of pulmonary stroma In secondary disease was determined.
Conclusion. For early diagnosis of pneumonia in myelotoxic agranulocytosis it is necessary to make examination by HRCT before BMT. HRCT of the chest is indicated in even minor changes in the clinical picture. It is necessary to perform a control over water-electrolyte balance and active respiratory exercise in the course of conditioning. Viral pneumonias show the picture of metainflammatory changes for a long time. Fungal pneumonias tend to recurrence at "previous site". HRCT examination of the pulmonary tissue provides more information about pulmonary tissue in patients with secondary disease.
作者简介
L Gotman
ГНЦ РАМНМосква; ГНЦ РАМН
I Kostina
ГНЦ РАМНМосква; ГНЦ РАМН
E Vishnevskaya
ГНЦ РАМНМосква; ГНЦ РАМН
D Togonidze
ГНЦ РАМНМосква; ГНЦ РАМН
L Mendeleeva
ГНЦ РАМНМосква; ГНЦ РАМН
L Lyubimova
ГНЦ РАМНМосква; ГНЦ РАМН
V Savchenko
ГНЦ РАМНМосква; ГНЦ РАМН
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