«Парадокс ожирения» и степень его доказанности
- Авторы: Миклишанская С.В.1, Мазур Н.А.1, Соломасова Л.В.1, Чигинева В.В.1
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Учреждения:
- ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
- Выпуск: Том 92, № 4 (2020)
- Страницы: 84-90
- Раздел: Оригинальные статьи
- URL: https://journals.rcsi.science/0040-3660/article/view/34112
- DOI: https://doi.org/10.26442/00403660.2020.04.000421
- ID: 34112
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Аннотация
В статье дана критическая оценка так называемого «парадокса ожирения». Освещены методические ошибки, которые встречаются при организации исследований, изучавших «парадокс ожирения», и формировании групп сравнения. Также приводятся примеры исчезновения «парадокса ожирения» при учете дополнительных факторов риска. Организация проспективных исследований или более тщательный учет всех известных на сегодняшний день факторов риска сердечно-сосудистых заболеваний (ССЗ) позволит существенно улучшить результаты изучения влияния избыточной массы тела и ожирения на смертность больных с ССЗ. Таким образом, несмотря на биологические возможности существования положительного влияния жировой ткани при ССЗ, наличие большого количества ошибок, выявленных при анализе работ, исследующих «парадокс ожирения», требует пересмотреть вопрос о существовании данного феномена, следует учитывать возможность того, что «парадокс ожирения» может быть следствием неправильного дизайна исследований для изучения данного явления.
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Софья Владимировна Миклишанская
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
Автор, ответственный за переписку.
Email: kvant83@list.ru
ORCID iD: 0000-0002-1009-099X
к.м.н., ассистент каф. кардиологии
Россия, МоскваНиколай Алексеевич Мазур
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
Email: kvant83@list.ru
ORCID iD: 0000-0003-0984-1562
д.м.н., проф., почетный зав. каф. кардиологии
Россия, МоскваЛилия Владимировна Соломасова
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
Email: kvant83@list.ru
ORCID iD: 0000-0001-8362-6946
ст. лаборант каф. кардиологии
Россия, МоскваВиктория Васильевна Чигинева
ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России
Email: kvant83@list.ru
ORCID iD: 0000-0002-9471-851X
д.м.н., доц. каф. кардиологии
Россия, МоскваСписок литературы
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