Ревматоидный артрит: достижения и нерешенные проблемы
- Авторы: Насонов Е.Л.1,2, Лила А.М.1
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Учреждения:
- ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»
- ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)
- Выпуск: Том 91, № 5 (2019)
- Страницы: 4-7
- Раздел: Передовая статья
- URL: https://journals.rcsi.science/0040-3660/article/view/33562
- DOI: https://doi.org/10.26442/00403660.2019.05.000259
- ID: 33562
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Несмотря на достигнутые успехи в лечении ревматоидного артрита (РА), связанные с разработкой новых лекарственных препаратов и совершенствованием стратегии лечения, позволяющих достигнуть ремиссии у многих пациентов, остается много теоретических и клинических проблем, касающихся как определения понятия «ремиссия», ее характеристики и типов, так и подходов к оптимальной тактике «симптоматической» и «патогенетической» лекарственной терапии на разных стадиях болезни, применение которой позволит быстро индуцировать состояние ремиссии и поддерживать ее в долгосрочной перспективе. Необходимы дальнейшие исследования, направленные на изучение природы гетерогенности патогенетических механизмов РА, подходов к ранней диагностике, совершенствование методов мониторинга активности заболевания, биомаркеров эффективности и резистентности к терапии и, наконец, разработки дифференцированной терапии, в том числе связанной с поиском новых «терапевтических» мишеней.
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Евгений Львович Насонов
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)
Email: nasonov@irramn.ru
акад. РАН, д.м.н., проф., научный руководитель ФГБНУ «НИИР им. В.А. Насоновой» Москва, Россия
Александр Михайлович Лила
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»д.м.н., проф., директор ФГБНУ «НИИР им. В.А. Насоновой» Москва, Россия
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