Жесткость сосудов и диастолическая сердечная недостаточность


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Аннотация

Аннотация. Жесткость сосудов рассматривается как результат дегенеративных процессов, потенцируемых старением, артериальной гипертонией и другими факторами риска. Одно из серьезных последствий высокой жесткости артерий - изменение центральной гемодинамики, что дает начало цепи событий в виде увеличения посленагрузки на левый желудочек, его концентрической гипертрофии, диастолической дисфункции и увеличивает общий риск развития сердечно-сосудистых осложнений. Цель обзора - обсуждение механизмов жесткости сосудов, фокусируя внимание на роль этого состояния в развитии хронической сердечной недостаточности с сохраненной фракцией выброса и в качестве будущей мишени ее патогенетического лечения.

Об авторах

О М Драпкина

Первый МГМУ им. И.М. Сеченова

Email: drapkina@bk.ru

А Н Кабурова

Первый МГМУ им. И.М. Сеченова

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