A family imported case of dengue fever. Case report

Dengue fever is the most common zoonotic infection with a transmissible mechanism of virus transmission in tropical and subtropical countries. In the first two decades of the 21st century, a significant increase in dengue fever cases was registered in more than 120 countries worldwide. The article presents a family imported case of dengue fever in a 34-year-old man and a 35-year-old woman who fell ill within 3 days after returning from Thailand (Phuket Island). In both cases, there was an acute onset of the disease with an increase in body temperature to (39–40°С), severe weakness, severe muscle and joint pain, severe headache, and loose stools once or twice. They were treated independently for acute respiratory infections. They sought medical help on the 4th and 5th days of their illness and were admitted to an infectious diseases hospital. The disease was accompanied by the development of posterior cervical and submandibular lymphadenitis, hepatomegaly, an uncommon spotty-papular rash on the skin of the trunk and arms, single point hemorrhages, severe thrombocytopenia and leukopenia. The woman was diagnosed with posterior cervical and submandibular lymphadenitis, and hepatosplenomegaly. On the 6th day of the disease, the woman was radiographically diagnosed with peribronchial edema of the interstitium. On the 7th day of the disease, the man developed a hydrocele on the right. Type 2 dengue virus was detected in blood, urine, and saliva by polymerase chain reaction in both patients. The man was discharged on the 20th day of his illness with asthenovegetative and dyspeptic symptoms that persisted for several weeks. The woman was discharged on the 17th day of her illness with residual asthenovegetative manifestations and secondary thrombocytopenia lasting several years.