Matrices of Ferromagnetic Microwires for the Control of Cellular Dynamics and Localized Delivery of Medicines
- Авторы: Beklemisheva A.1,2, Yudanov N.1, Gurevich A.1,2, Panina L.1,2,3, Zablotskiy V.4, Deyneka A.4
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Учреждения:
- National University of Science and Technology MISiS
- Moscow State Institute of Electronic Engineering (Technical University)
- Kant Baltic Federal University
- Institute of Physics, Academy of Sciences of the Czech Republic
- Выпуск: Том 120, № 6 (2019)
- Страницы: 556-562
- Раздел: Electrical and Magnetic Properties
- URL: https://journals.rcsi.science/0031-918X/article/view/168526
- DOI: https://doi.org/10.1134/S0031918X19060036
- ID: 168526
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Аннотация
Amorphous ferromagnetic microwires are quite promising for use in various biomedical fields. A microwire in a biocompatible shell can be introduced into soft tissues or into blood vessels to maintain the biofunctioning of magnetic nanoparticles or stem cells with magnetic markers circulating in the blood. The magnetic fields created by the lattices of microwires are characterized by strong spatial gradients and can change over time in a specified manner. Such fields are necessary for the development of various magnetophoretic analytical chips for controlling the kinetics of cells and also for controlled drug delivery. A system of diametrically magnetized microwires is suggested in this paper, which possesses an energy minimum necessary for the stable capture of diamagnetic cells. The suggested dipole system is also promising for the accelerated diffusion transfer of magnetic nanoparticles, which are located in a liquid carrier, due to a gradient magnetic field.
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Об авторах
A. Beklemisheva
National University of Science and Technology MISiS; Moscow State Institute of Electronic Engineering (Technical University)
Автор, ответственный за переписку.
Email: AnnaBekl@ya.ru
Россия, Moscow, 119049; Zelenograd, Moscow oblast, 124681
N. Yudanov
National University of Science and Technology MISiS
Email: AnnaBekl@ya.ru
Россия, Moscow, 119049
A. Gurevich
National University of Science and Technology MISiS; Moscow State Institute of Electronic Engineering (Technical University)
Email: AnnaBekl@ya.ru
Россия, Moscow, 119049; Zelenograd, Moscow oblast, 124681
L. Panina
National University of Science and Technology MISiS; Moscow State Institute of Electronic Engineering (Technical University); Kant Baltic Federal University
Email: AnnaBekl@ya.ru
Россия, Moscow, 119049; Zelenograd, Moscow oblast, 124681; Kaliningrad, 236016
V. Zablotskiy
Institute of Physics, Academy of Sciences of the Czech Republic
Email: AnnaBekl@ya.ru
Чехия, Na Slovance 2, Praha 8, CZ-182 21
A. Deyneka
Institute of Physics, Academy of Sciences of the Czech Republic
Email: AnnaBekl@ya.ru
Чехия, Na Slovance 2, Praha 8, CZ-182 21