Localization of inhomogeneities in diffuse optical tomography based on late arriving photons

Abstract

An algorithm for localizing inhomogeneities in pulsed diffuse optical tomography is proposed and implemented. A distinctive feature of this technique is the formation of an initial approximation to the spatial distributions of the absorption and scattering coefficients in a biomedical object under study based on the angle-dependent homogeneity index, HI(a). The method allows one to determine the approximate optical structure of the object using late arriving photons and thus solve more rapidly the inverse problem. The suggestion that all absorbing and scattering inhomogeneities in an object under study are spherical also simplifies and enhances image reconstruction.