Production of chiral matrices with hybrid silver–thiocholesterol nanosystems and study of their properties

Abstract

A new type of chiral matrix based on silver–thiocholesterol hybrid nanosystems adsorbed on silica gel has been proposed. The molar ratio of stabilized thiocholesterol (L) ligand and silver (Ag) was found to have little effect on the size of the resulting silver nanoparticles (SNPs). The average diameter of SNPs was 2.7 ± 0.4, 2.2 ± 0.4, and 2.1 ± 0.6 nm upon the ratios Ag: L = 1: 5, Ag: L = 1: 2, and Ag: L = 1: 0.5, respectively. The resulting chiral matrices possess enantioselectivity relative to the 1,1’-binaphthyl-2,2’-diamine (BNDA) and trifluoroanthranyl ethanol (TFAE) optical isomers. The TFAE optical isomers were successfully separated using thin layer chromatography (α = 1.56).