Key molecular mechanisms associated with cell malignant transformation in acute myeloid leukemia
- Авторы: Orlova N.N.1, Lebedev T.D.1, Spirin P.V.1, Prassolov V.S.1
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Учреждения:
- Engelhardt Institute of Molecular Biology
- Выпуск: Том 50, № 3 (2016)
- Страницы: 344-352
- Раздел: Reviews
- URL: https://journals.rcsi.science/0026-8933/article/view/162648
- DOI: https://doi.org/10.1134/S0026893316020187
- ID: 162648
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Аннотация
Cancer, along with cardiovascular disorders, is one of the most important problems of healthcare. Pathologies of the hematopoietic system are the most prevalent in patients under 30 years of age, including acute myeloid leukemia (AML), which is widespread and difficult to treat. The review considers the mechanisms that play a significant role in AML cell malignant transformation and shows the contributions of certain genes to both remission and resistance of AML cells to various treatments.
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Об авторах
N. Orlova
Engelhardt Institute of Molecular Biology
Email: prassolov45@mail.ru
Россия, Moscow, 119991
T. Lebedev
Engelhardt Institute of Molecular Biology
Email: prassolov45@mail.ru
Россия, Moscow, 119991
P. Spirin
Engelhardt Institute of Molecular Biology
Email: prassolov45@mail.ru
Россия, Moscow, 119991
V. Prassolov
Engelhardt Institute of Molecular Biology
Автор, ответственный за переписку.
Email: prassolov45@mail.ru
Россия, Moscow, 119991
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