Targeted Bifunctional Proteins and Hybrid Nanoconstructs for Cancer Diagnostics and Therapies
- Авторы: Deyev S.M.1,2, Lebedenko E.N.1
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Учреждения:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
- Lobachevsky State University of Nizhny Novgorod
- Выпуск: Том 51, № 6 (2017)
- Страницы: 788-803
- Раздел: Current Trends in the Application of Monoclonal Antibodies Special Issue
- URL: https://journals.rcsi.science/0026-8933/article/view/163288
- DOI: https://doi.org/10.1134/S002689331706005X
- ID: 163288
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Аннотация
In this review, the authors' works published within the past 5 years devoted to the development of bifunctional hybrid nanostructures based on the targeting polypeptides and nanoparticles of various origin (quantum dots, nanogold, nanodiamonds, upconversion nanoparticles, magnetic and polymer nanoparticles) as modules that ensure visualization and various damaging effects on cancer cells are surveyed and the prospects of their application in theranostics and precision medicine have been contemplated.
Об авторах
S. Deyev
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry; Lobachevsky State University of Nizhny Novgorod
Email: elebedenko@mail.ru
Россия, Moscow, 117997; Nizhny Novgorod, 603950
E. Lebedenko
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
Автор, ответственный за переписку.
Email: elebedenko@mail.ru
Россия, Moscow, 117997
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