Chronic pancreatitis. Familiar stranger. Peculiarities of etiology, pathogenesis, clinic, diagnosis and treatment at the current stage of evidence-based medicine

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Resumo

The review of the information about etiology, pathogenesis, modern diagnostic criteria and management tactics of patients with chronic pancreatitis is carried out. Research data concerning the criterion validity of the diagnosis and modern standards of complex treatment are presented.

Sobre autores

Evgenia Zinovieva

OOO «Medi-Pro» «SM-Clinic» at Dunayskiy pr.

Autor responsável pela correspondência
Email: enzinovyeva@mail.ru
ORCID ID: 0000-0001-7859-7124

Candidate of Medical Sciences, Associate Professor, Gastroenterologist

Rússia, Saint Petersburg

Natalia Varlamova

AVA-PETER LLC, Scandinavia clinic

Email: topsi2005@mail.ru
ORCID ID: 0000-0002-9905-4089

Ultrasound Doctor

Rússia, Saint Petersburg

Olga Dedkova

OOO «Medi-Pro» «SM-Clinic» at Dunayskiy pr.

Email: O_dedkova07@mail.ru

Chief Physician, Gastroenterologist

Rússia, Saint Petersburg

Bibliografia

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  2. Xiao A.Y., Tan M.L., Wu L.M. et al. Global incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies. The lancet Gastroenterology & hepatology. 2016;1(1):45–55.
  3. Ивашкин В.Т., Маев И.В., Охлобыстин А.В. и др. Рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению хронического панкреатита. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2014; 4(24): 70–97
  4. Etemad B., Whitcomb D.C. Chronic Pancreatitis: Diagnosis, Classification, and New Genetic Developments. Gastroenterology. 2001;120(3): 682–707).
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  9. Zhu X, Liu D, Wei Q, Lin H, Zhi M, Chen Y, et al. New-Onset Diabetes Mellitus After Chronic Pancreatitis Diagnosis: A Systematic Review and Meta-analysis. Pancreas. 2019;48(7):868–875.
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  17. Whitcomb D.C., Lehman G.A., Vasileva G. et al. Pancrelipase delayed-release capsules (CREON) for exocrine pancreatic insufficiency due to chronic pancreatitis or pancreatic surgery: A double-blind randomized trial. The American journal of gastroenterology. 2010;105(10):2276–2286.

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1. JATS XML
2. Pic. 1. Irregularity of the Virsung’s duct, irregular contours of the pancreas, increased echogenicity, heterogeneous structure

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3. Pic. 2. uneven size of pancreas: head – 31 mm (enlarged), body – 18 mm and tail – 18 mm

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4. Pic. 3. Irregularity of contours, heterogeneity of structure, increased echogenicity

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5. Pic. 4. uneven size (tail thickened), virsung duct is not dilated, wall is thickened

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6. Pic. 5. Calcinates in the head and body

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7. Pic. 6. Compression elastography of the pancreas. Mosaic type of elastogram with a predominance of blue mapping: the density of the pancreas is diffusely increased

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