Advances in Chemical PhysicsAdvances in Chemical PhysicsФизиология растений0015-33033034-624XThe Russian Academy of Sciences26188110.31857/S0015330324020024OBXANCОБЗОРЫReview ArticleГенетические механизмы регуляции обновления клеток корневого чехлика у Arabidopsis thaliana L.Генетические механизмы регуляции обновления клеток корневого чехлика у Arabidopsis thaliana L.ЧеренкоВ. А.
Russian Federation
ezemlyanskaya@bionet.nsc.ruОмельянчукН. А.
Russian Federation
ezemlyanskaya@bionet.nsc.ruЗемлянскаяЕ. В.
Russian Federation
ezemlyanskaya@bionet.nsc.ruФедеральное государственное бюджетное научное учреждение “Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук”Федеральное государственное автономное образовательное учреждение высшего образования “Новосибирский национальный исследовательский государственный университет”Федеральное государственное бюджетное научное учреждение “Федеральный исследовательский центр Институт цитологии и генетики Сибирского отделения Российской академии наук”Федеральное государственное автономное образовательное учреждение высшего образования “Новосибирский национальный исследовательский государственный университет”150320247121351481608202416082024Copyright ©; 2024, Russian Academy of SciencesCopyright ©; 2024, Российская академия наук2024Russian Academy of SciencesРоссийская академия наукhttps://journals.rcsi.science/0015-3303/article/view/261881

Синхронизация пространственно разобщенных процессов деления и потери клеток играет первостепенную роль в обновлении и поддержании структуры органов и тканей, но о генетических механизмах ее регуляции на данный момент известно очень немного. У растений быстрому обновлению подвержен корневой чехлик, который располагается на кончике корня, защищая от механических повреждений нишу стволовых клеток и выполняя ряд других важных функций. Несмотря на непрерывное поступление и дифференцировку дочерних клеток от деления инициалей (стволовых клеток), корневой чехлик не увеличивается в размерах благодаря регулярному удалению дифференцированных клеток на внешнем его конце. Для строгого поддержания постоянства размера корневого чехлика важно, чтобы деления стволовых клеток были синхронизированы с удалением клеток внешнего слоя. У Arabidopsis thaliana, модельного объекта генетики растений, корневой чехлик имеет очень простую упорядоченную структуру, а слущивание старых клеток происходит единым слоем, что делает этот вид удобной моделью для исследования механизмов регуляции обновления клеток корневого чехлика. В обзоре рассмотрено поддержание гомеостаза структуры и размера корневого чехлика у A. thaliana, обсуждены данные по генетическому контролю этого процесса и возможные перспективные направления дальнейших исследований в этой области.

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