Biological Xenogenic Vessel Prostheses: Effect of H2O/CO2 and EtOH Media on the Structure and Mechanical Properties of the Bovine Jugular Veins


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The effect of the H2O/CO2 and EtOH/CO2 media at pressures and temperatures corresponding to the formation of supercritical (sc) carbon dioxide on the structure and mechanical properties of bovine jugular veins was studied for the first time. Treatment of bovine jugular veins in an sc-CO2 + ethanol or sc-CO2 + water medium considerably devitalized the tissue and increased the tissue elasticity, which allows considering the treated veins as promising vascular grafts with expected high capacity to suppress calcification and good hemodynamic properties.

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I. Chashchin

Nesmeyanov Institute of Organoelement Compounds

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Email: chaschin@polly.phys.msu.ru
俄罗斯联邦, Moscow, 119991

N. Bakuleva

Bakulev Scientific Center of Cardiovascular Surgery

Email: chaschin@polly.phys.msu.ru
俄罗斯联邦, Moscow, 121552

T. Grigor’ev

Nesmeyanov Institute of Organoelement Compounds; National Research Center “Kurchatov Institute”

Email: chaschin@polly.phys.msu.ru
俄罗斯联邦, Moscow, 119991; Moscow, 123182

S. Krasheninnikov

National Research Center “Kurchatov Institute”

Email: chaschin@polly.phys.msu.ru
俄罗斯联邦, Moscow, 123182

C. Abramchuk

Nesmeyanov Institute of Organoelement Compounds

Email: chaschin@polly.phys.msu.ru
俄罗斯联邦, Moscow, 119991

K. Dzhidzhikhiya

Bakulev Scientific Center of Cardiovascular Surgery

Email: chaschin@polly.phys.msu.ru
俄罗斯联邦, Moscow, 121552

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