Production of a Novel Material Based on a Collagen–Chitosan Composite and Ibuprofen in a Supercritical Medium

E. E. Said-Galiev; M. S. Rubina; A. V. Naumkin; N. S. Ikonnikov; A. Yu. Vasil’kov

doi:10.1134/S0012501618090038

Production of a Novel Material Based on a Collagen–Chitosan Composite and Ibuprofen in a Supercritical Medium

Authors: Said-Galiev E.E.¹, Rubina M.S.¹, Naumkin A.V.¹, Ikonnikov N.S.¹, Vasil’kov A.Y.¹
Affiliations:
1. Nesmeyanov Institute of Organoelement Compounds
Issue: Vol 482, No 1 (2018)
Pages: 130-133
Section: Physical Chemistry
URL: https://journals.rcsi.science/0012-5016/article/view/153906
DOI: https://doi.org/10.1134/S0012501618090038
ID: 153906

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Abstract

A novel material for biomedical applications was obtained from a collagen–chitosan composite and ibuprofen by a fluid process using supercritical carbon dioxide. The material was characterized by IR and X-ray photoelectron spectroscopy. The applicability of XPS analysis of biomaterials for quantification of loaded therapeutic agents is demonstrated.