Analysis of the Intensity of Apoptosis in Rat Organs at Various Stages of Ontogeny


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Activity of apoptosis in the thymus, liver, and kidneys on days 20, 22, 35, 50, 80, 110, and 140 of ontogeny was studied in the experiments on rats using the alkaline gel electrophoresis and flow cytofluorometry. Changes in apoptosis intensity depended on animal age. The maximum level of this parameter was observed on day 20 of ontogeny with the following reduction in this parameter to the minimum value on days 35-50. Then it gradually increased up to relatively high levels on day 110 and significantly reduced by day 140.

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N. Tyshko

Federal Research Center of Nutrition and Biotechnology

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Email: tnv@ion.ru
俄罗斯联邦, Moscow

E. Sadykova

Federal Research Center of Nutrition and Biotechnology

Email: tnv@ion.ru
俄罗斯联邦, Moscow

S. Shestakova

Federal Research Center of Nutrition and Biotechnology

Email: tnv@ion.ru
俄罗斯联邦, Moscow

E. Trushina

Federal Research Center of Nutrition and Biotechnology

Email: tnv@ion.ru
俄罗斯联邦, Moscow

O. Mustafina

Federal Research Center of Nutrition and Biotechnology

Email: tnv@ion.ru
俄罗斯联邦, Moscow

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