Ultrastructural Characteristics of the Testicular Interstitial Endocrinocytes of Adult Rats Subjected to Total Sialoadenectomy
- 作者: Ivanova V.1, Mil’to I.1,2, Sukhodolo I.1, Miller A.1
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隶属关系:
- Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of Russia
- Department of Biotechnology and Organic Chemistry, Tomsk National Research Polytechnological University
- 期: 卷 165, 编号 2 (2018)
- 页面: 280-283
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240227
- DOI: https://doi.org/10.1007/s10517-018-4148-0
- ID: 240227
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详细
The major salivary glands of rats release into the saliva and blood a wide spectrum of bioactive substances, essential for many organs, including the testes. Sialoadenectomy leads to the development of degenerative changes in the cells of the twisted testicular tubules. However, the effects of bioactive factors released by the major salivary glands on the morphology and function of Leydig cells remain little studied. Sialoadenectomy in adult rats led (in 1-4 weeks) to a decrease in the nuclear and cytoplasmatic areas of Leydig cells, violation of the plasmalemma integrity, dilatation of perinuclear space and agranular endoplasmatic reticulum vesicles, and to destruction of the mitochondria. Ultrastructural changes caused by sialoadenectomy completely resolved by week 6 of the experiment at the expense of compensatory activation of the synthesis of the major salivary gland factors by other sources in the organism of rats.
作者简介
V. Ivanova
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of Russia
编辑信件的主要联系方式.
Email: ivvera92@rambler.ru
俄罗斯联邦, Tomsk
I. Mil’to
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of Russia; Department of Biotechnology and Organic Chemistry, Tomsk National Research Polytechnological University
Email: ivvera92@rambler.ru
俄罗斯联邦, Tomsk; Tomsk
I. Sukhodolo
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of Russia
Email: ivvera92@rambler.ru
俄罗斯联邦, Tomsk
A. Miller
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of Health of Russia
Email: ivvera92@rambler.ru
俄罗斯联邦, Tomsk