Effect of GlcNAc-, Man- and Gal-Specific Lectins of the Cytosol, Nuclear Membrane, and Nuclear Matrix of Calf Brain Cortex on Proliferation Activity of Peripheral Blood Lymphocyte
- 作者: Macharadze T.1, Akhalkatsi R.1
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隶属关系:
- Ivane Javakhishvili Tbilisi State University
- 期: 卷 163, 编号 3 (2017)
- 页面: 338-339
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238869
- DOI: https://doi.org/10.1007/s10517-017-3798-7
- ID: 238869
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详细
We studied the effect of GlcNAc-, Man-, and Gal-specific lectins isolated from cell cytosol, nuclear membrane, and nuclear matrix of calf brain cortex, lyophilized, and stored for 5 years on proliferation activity of human peripheral blood lymphocytes and on hemagglutination activity of trypsinized rabbit erythrocytes. Human peripheral blood lymphocytes treated lyophilized lectins demonstrated lower proliferation activity than lymphocytes treated with concanavalin A (positive control), but higher than control lymphocytes (incubated with saline). Lectins produced no effect on hemagglutination activity.
作者简介
T. Macharadze
Ivane Javakhishvili Tbilisi State University
Email: rusudanakhalkatsi@yahoo.com
格鲁吉亚, Tbilisi
R.G. Akhalkatsi
Ivane Javakhishvili Tbilisi State University
编辑信件的主要联系方式.
Email: rusudanakhalkatsi@yahoo.com
格鲁吉亚, Tbilisi
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