Effect of New Antiviral Agent Camphecin on Behavior of Mice
- 作者: Babina A.1, Lavrinenko V.1, Yarovaya O.1,2, Salakhutdinov N.1,2
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隶属关系:
- Novosibirsk National Research State University
- N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Division of Russian Academy of Sciences
- 期: 卷 162, 编号 3 (2017)
- 页面: 346-348
- 栏目: Pharmacology and Toxicology
- URL: https://journals.rcsi.science/0007-4888/article/view/238192
- DOI: https://doi.org/10.1007/s10517-017-3612-6
- ID: 238192
如何引用文章
详细
We studied the effect of camphecin (1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene-aminoethanol) on mouse behavior in the open-field test. Camphecin possesses antiviral activity and inhibits viral replication, but its influence on the nervous system is poorly studied. Single camphecin injection produced no significant changes in behavioral patterns. Chronic camphecin administration (5 times over 2 weeks) to mice of different strains had no significant influence on open field behavior (motor, exploratory activity, anxiety, emotional state and vegetative functions). The findings are discussed in the context of neutral influence of camphecin on animal behavior.
作者简介
A. Babina
Novosibirsk National Research State University
Email: igor@academ.org
俄罗斯联邦, Novosibirsk
V. Lavrinenko
Novosibirsk National Research State University
编辑信件的主要联系方式.
Email: igor@academ.org
俄罗斯联邦, Novosibirsk
O. Yarovaya
Novosibirsk National Research State University; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Division of Russian Academy of Sciences
Email: igor@academ.org
俄罗斯联邦, Novosibirsk; Novosibirsk
N. Salakhutdinov
Novosibirsk National Research State University; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Division of Russian Academy of Sciences
Email: igor@academ.org
俄罗斯联邦, Novosibirsk; Novosibirsk
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