Recombination of Correlations between Bioelements in the Liver and Lungs during Modeling of Diet-Induced Obesity
- 作者: Manvelidze R.1, Churin B.1, Trunova V.2,3, Sidorina A.2, Zvereva V.2, Astashov V.4, Preobrazhenskaya V.1
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隶属关系:
- Institute of Molecular Pathology and Pathomorphology
- A. V. Nikolaev Institute of Inorganic Chemistry, Siberian Division of the Russian Academy of Sciences
- Novosibirsk National Research State University
- Research Institute of Chemical Diversity
- 期: 卷 160, 编号 3 (2016)
- 页面: 308-312
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236694
- DOI: https://doi.org/10.1007/s10517-016-3158-z
- ID: 236694
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详细
In rats with obesity induced by high fat ration, the concentrations of K, Ca, Mn, Fe, Cu, Zn, Se, Br, Rb, and Sr were measured in the liver and lungs using synchrotron X-ray fluorescence analysis. Recombinations of inter-element correlations in the liver and lungs of rats receiving or not receiving additional Zn were observed under fasting conditions and after eating lard. Sr and Ca made the most pronounced contribution in the redistribution of correlations in the liver of obese rats. In contrast to other bioelements, Sr had negative correlations with all study elements in the liver of obese rats during physiological starvation. Long-term administration of Zn to rats was followed by recombination of both fasting and postprandial inert-element correlations in the liver and lungs, but Zn concentration did not change under these conditions. Redistribution of correlations in the liver and lungs of obese rats under fasting conditions reflects fundamental changes in metabolic processes, while redistribution observed after fat meal indicates temporary (postprandial) changes.
作者简介
R. Manvelidze
Institute of Molecular Pathology and Pathomorphology
Email: pathol@inbox.ru
俄罗斯联邦, Moscow
B. Churin
Institute of Molecular Pathology and Pathomorphology
编辑信件的主要联系方式.
Email: pathol@inbox.ru
俄罗斯联邦, Moscow
V. Trunova
A. V. Nikolaev Institute of Inorganic Chemistry, Siberian Division of the Russian Academy of Sciences; Novosibirsk National Research State University
Email: pathol@inbox.ru
俄罗斯联邦, Moscow; Novosibirsk
A. Sidorina
A. V. Nikolaev Institute of Inorganic Chemistry, Siberian Division of the Russian Academy of Sciences
Email: pathol@inbox.ru
俄罗斯联邦, Moscow
V. Zvereva
A. V. Nikolaev Institute of Inorganic Chemistry, Siberian Division of the Russian Academy of Sciences
Email: pathol@inbox.ru
俄罗斯联邦, Moscow
V. Astashov
Research Institute of Chemical Diversity
Email: pathol@inbox.ru
俄罗斯联邦, Moscow
V. Preobrazhenskaya
Institute of Molecular Pathology and Pathomorphology
Email: pathol@inbox.ru
俄罗斯联邦, Moscow
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