Formation of Neural Networks in 3D Scaffolds Fabricated by Means of Laser Microstereolithography
- Авторы: Vedunova M.1,2, Timashev P.3, Mishchenko T.1,2, Mitroshina E.1,2, Koroleva A.3, Chichkov B.3, Panchenko V.3, Bagratashvili V.3, Mukhina I.1,2
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Учреждения:
- N. I. Lobachevsky Nizhny Novgorod State University
- Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
- Institute of Laser and Information Technologies, Russian Academy of Sciences
- Выпуск: Том 161, № 4 (2016)
- Страницы: 616-621
- Раздел: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/237625
- DOI: https://doi.org/10.1007/s10517-016-3470-7
- ID: 237625
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Аннотация
We developed and tested new 3D scaffolds for neurotransplantation. Scaffolds of predetermined architectonic were prepared using microstereolithography technique. Scaffolds were highly biocompatible with the nervous tissue cells. In vitro studies showed that the material of fabricated scaffolds is not toxic for dissociated brain cells and promotes the formation of functional neural networks in the matrix. These results demonstrate the possibility of fabrication of tissue-engineering constructs for neurotransplantation based on created scaffolds.
Об авторах
M. Vedunova
N. I. Lobachevsky Nizhny Novgorod State University; Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: mvedunova@yandex.ru
Россия, Nizhny Novgorod; Nizhny Novgorod
P. Timashev
Institute of Laser and Information Technologies, Russian Academy of Sciences
Email: mvedunova@yandex.ru
Россия, Moscow
T. Mishchenko
N. I. Lobachevsky Nizhny Novgorod State University; Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
Email: mvedunova@yandex.ru
Россия, Nizhny Novgorod; Nizhny Novgorod
E. Mitroshina
N. I. Lobachevsky Nizhny Novgorod State University; Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
Email: mvedunova@yandex.ru
Россия, Nizhny Novgorod; Nizhny Novgorod
A. Koroleva
Institute of Laser and Information Technologies, Russian Academy of Sciences
Email: mvedunova@yandex.ru
Россия, Moscow
B. Chichkov
Institute of Laser and Information Technologies, Russian Academy of Sciences
Email: mvedunova@yandex.ru
Россия, Moscow
V. Panchenko
Institute of Laser and Information Technologies, Russian Academy of Sciences
Email: mvedunova@yandex.ru
Россия, Moscow
V. Bagratashvili
Institute of Laser and Information Technologies, Russian Academy of Sciences
Email: mvedunova@yandex.ru
Россия, Moscow
I. Mukhina
N. I. Lobachevsky Nizhny Novgorod State University; Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
Email: mvedunova@yandex.ru
Россия, Nizhny Novgorod; Nizhny Novgorod
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