3111T/C Clock Gene Polymorphism in Women with Insomnia
- Autores: Semenova N.1, Madaeva I.1, Bairova T.1, Ershova O.1, Kalyuzhnaya O.1, Korytov L.1, Kolesnikova L.1
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Afiliações:
- Research Center of Family Health and Human Reproduction Problems
- Edição: Volume 163, Nº 4 (2017)
- Páginas: 461-464
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238991
- DOI: https://doi.org/10.1007/s10517-017-3828-5
- ID: 238991
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Resumo
Comparative analysis of the frequency distributions of genotypes and alleles of 3111T/C Clock gene polymorphism was carried out in climacteric Caucasian women with and without insomnia. Genotype TT is more incident in women with insomnia (55.5% vs. 42.6% in the control). Allele T predominated in the control and study group and its frequency is higher in women with insomnia. The OR for the risk of insomnia realization is 1.78 (95%CI 1.16-2.75). No association between genotypes and complaints of patients with insomnia is detected.
Sobre autores
N. Semenova
Research Center of Family Health and Human Reproduction Problems
Autor responsável pela correspondência
Email: natkor_84@mail.ru
Rússia, Irkutsk
I. Madaeva
Research Center of Family Health and Human Reproduction Problems
Email: natkor_84@mail.ru
Rússia, Irkutsk
T. Bairova
Research Center of Family Health and Human Reproduction Problems
Email: natkor_84@mail.ru
Rússia, Irkutsk
O. Ershova
Research Center of Family Health and Human Reproduction Problems
Email: natkor_84@mail.ru
Rússia, Irkutsk
O. Kalyuzhnaya
Research Center of Family Health and Human Reproduction Problems
Email: natkor_84@mail.ru
Rússia, Irkutsk
L. Korytov
Research Center of Family Health and Human Reproduction Problems
Email: natkor_84@mail.ru
Rússia, Irkutsk
L. Kolesnikova
Research Center of Family Health and Human Reproduction Problems
Email: natkor_84@mail.ru
Rússia, Irkutsk