High Potassium Concentration during Culturing of Early Mammalian Embryos: Normal or Extreme Situation?
- Autores: Pogorelov A.1, Smirnov A.1, Pogorelova V.1
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Afiliações:
- Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
- Edição: Volume 163, Nº 1 (2017)
- Páginas: 163-168
- Seção: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/238727
- DOI: https://doi.org/10.1007/s10517-017-3758-2
- ID: 238727
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Resumo
Analysis of the element composition of oviduct and uterine fluid in mammals showed high potassium concentrations in the early embryo microenvironment in vivo. The results of early embryogenesis of mammals in vitro in the presence of high potassium concentrations are discussed. The data are summarized in accordance with the conditions of experimentally modeled pre-implantation development. Comparative assessment of the quality of embryo development until the blastocyst stage in vitro proved the embryos more successfully developed at potassium concentrations close to those registered in the oviductal fluid.
Sobre autores
A. Pogorelov
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Autor responsável pela correspondência
Email: agpogorelov@rambler.ru
Rússia, Pushchino
A. Smirnov
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: agpogorelov@rambler.ru
Rússia, Pushchino
V. Pogorelova
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: agpogorelov@rambler.ru
Rússia, Pushchino