Мақаланы E-mail арқылы жіберу Effect of Non-Thermal Plasma on Proliferative Activity and Adhesion of Multipotent Stromal Cells to Scaffolds Developed for Tissue-Engineered Constructs
- Авторлар: Chailakhyan R.1,2,3, Grosheva A.1, Gerasimov Y.1, Vorob’eva N.2, Ermolaeva S.1,4, Sysolyatina E.1, Kazakova M.1, Akishev Y.5, Petryakov A.5, Sidoruk K.6, Burdukovskii V.7, Timashev P.2,3,8
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Мекемелер:
- N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
- Institute of Photonic Technologies, Federal Research Center for Crystallography and Photonics, Russian Academy of Sciences
- Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University
- Moscow Institute of Physics and Technology
- Troitsk Institute for Innovation and Fusion Research
- Laboratory of Protein Engineering, State Research Institute of Genetics and Selection of Industrial Microorganisms, National Research Center Kurchatov Institute
- Baikal Institute of Nature Management, Siberian Division of the Russian Academy of Science
- Department of Polymers and Composite Materials, N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences
- Шығарылым: Том 167, № 1 (2019)
- Беттер: 182-188
- Бөлім: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/241566
- DOI: https://doi.org/10.1007/s10517-019-04486-0
- ID: 241566
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
We studied the effect of non-thermal argon plasma on proliferative activity of bone marrow multipotent stromal cells in vitro. Treatment of stromal cell suspension with pure argon did not affect their proliferation. The cells treated with non-thermal argon plasma and explanted in the treatment medium demonstrated growth inhibition by 30-40% in comparison with the control. Multipotent stromal cells treated with plasma and after centrifugation explanted in normal medium within 12 min demonstrated accelerated growth. The total cell growth from the pellet and supernatant significantly exceeded the control values. We also analyzed adhesion and proliferative activity of multipotent stromal cells treated with non-thermal plasma on bioresorbable carriers. The cells adhered and proliferated on all types of studied samples. Adhesion properties of scaffolds differed. Caprolactone was found to be the most suitable material for adhesion and proliferation of multipotent stromal cells.
Авторлар туралы
R. Chailakhyan
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation; Institute of Photonic Technologies, Federal Research Center for Crystallography and Photonics, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University
Хат алмасуға жауапты Автор.
Email: rubenchail@yandex.ru
Ресей, Moscow; Moscow; Moscow
A. Grosheva
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow
Yu. Gerasimov
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow
N. Vorob’eva
Institute of Photonic Technologies, Federal Research Center for Crystallography and Photonics, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Ресей, Moscow
S. Ermolaeva
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation; Moscow Institute of Physics and Technology
Email: rubenchail@yandex.ru
Ресей, Moscow; Moscow
E. Sysolyatina
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow
M. Kazakova
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow
Yu. Akishev
Troitsk Institute for Innovation and Fusion Research
Email: rubenchail@yandex.ru
Ресей, Troitsk
A. Petryakov
Troitsk Institute for Innovation and Fusion Research
Email: rubenchail@yandex.ru
Ресей, Troitsk
K. Sidoruk
Laboratory of Protein Engineering, State Research Institute of Genetics and Selection of Industrial Microorganisms, National Research Center Kurchatov Institute
Email: rubenchail@yandex.ru
Ресей, Moscow
V. Burdukovskii
Baikal Institute of Nature Management, Siberian Division of the Russian Academy of Science
Email: rubenchail@yandex.ru
Ресей, Ulan-Ude, Republic of Buryatia
P. Timashev
Institute of Photonic Technologies, Federal Research Center for Crystallography and Photonics, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University; Department of Polymers and Composite Materials, N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Ресей, Moscow; Moscow; Moscow
