Antibacterial Activity of L-Lysine-α-Oxidase from the Trichoderma
- Authors: Smirnova I.P.1, Karimova E.V.1, Shneider Y.A.1
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Affiliations:
- T. T. Berezov Department of Biochemistry, Medical Faculty of the Medical Institute, the Peoples’ Friendship University of Russia
- Issue: Vol 163, No 6 (2017)
- Pages: 777-779
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239249
- DOI: https://doi.org/10.1007/s10517-017-3901-0
- ID: 239249
Cite item
Abstract
We studied the effects of a concentrate of metabolites of Trichoderma harzianum Rifai F-180, an active producer of L-lysine-α-oxidase, and homogenous enzyme on a highly virulent bacteria Erwinia amylovora. The producer of antitumor and antiviral Trichoderma enzyme L-lysine-α-oxidase was cultured on a processing system of G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences (Pushchino). Activity of L-lysine-α-oxidase in the prepared concentrate of metabolic products of the producer was 5.4 U/ml, and activity of the homogenous enzyme was 50 U/ml. Antibacterial activity of the enzyme was shown in our experiments.
About the authors
I. P. Smirnova
T. T. Berezov Department of Biochemistry, Medical Faculty of the Medical Institute, the Peoples’ Friendship University of Russia
Author for correspondence.
Email: smir-ip@yandex.ru
Russian Federation, Moscow
E. V. Karimova
T. T. Berezov Department of Biochemistry, Medical Faculty of the Medical Institute, the Peoples’ Friendship University of Russia
Email: smir-ip@yandex.ru
Russian Federation, Moscow
Yu. A. Shneider
T. T. Berezov Department of Biochemistry, Medical Faculty of the Medical Institute, the Peoples’ Friendship University of Russia
Email: smir-ip@yandex.ru
Russian Federation, Moscow