Email this article Design of Nanosomal Form of Aprotinin
- Authors: Kulikov O.A.1, Pyataev N.A.1, Zaborovskii A.V.2, Maev I.V.1, Ageev V.P.1, Marochkina E.E.1, Dolgacheva I.S.1, Avdyushkina I.S.1, Kokorev A.V.3, Gurevich K.G.2, Tatarina L.A.2, Yunina D.V.2
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Affiliations:
- N. P. Ogarev Mordovia National Research State University
- A. I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia
- Obninsk Institute for Nuclear Power Engineering of the National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
- Issue: Vol 163, No 6 (2017)
- Pages: 742-744
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239227
- DOI: https://doi.org/10.1007/s10517-017-3893-9
- ID: 239227
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Abstract
Liposomes containing aprotinin were produced by the phase inversion technique and purified by gel filtration. Aprotinin inclusion was assessed fluorescence labeling of the protein. The size of obtained liposomes was 212±35 nm and aprotinin concentration in the liposomal suspension was 3000 KIU/ml. The efficiency of aprotinin inclusion into liposomes was 31.9%.
About the authors
O. A. Kulikov
N. P. Ogarev Mordovia National Research State University
Email: azabor@mail.ru
Russian Federation, Saransk, the Republic of Mordovia
N. A. Pyataev
N. P. Ogarev Mordovia National Research State University
Email: azabor@mail.ru
Russian Federation, Saransk, the Republic of Mordovia
A. V. Zaborovskii
A. I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia
Author for correspondence.
Email: azabor@mail.ru
Russian Federation, Moscow
I. V. Maev
N. P. Ogarev Mordovia National Research State University
Email: azabor@mail.ru
Russian Federation, Saransk, the Republic of Mordovia
V. P. Ageev
N. P. Ogarev Mordovia National Research State University
Email: azabor@mail.ru
Russian Federation, Saransk, the Republic of Mordovia
E. E. Marochkina
N. P. Ogarev Mordovia National Research State University
Email: azabor@mail.ru
Russian Federation, Saransk, the Republic of Mordovia
I. S. Dolgacheva
N. P. Ogarev Mordovia National Research State University
Email: azabor@mail.ru
Russian Federation, Saransk, the Republic of Mordovia
I. S. Avdyushkina
N. P. Ogarev Mordovia National Research State University
Email: azabor@mail.ru
Russian Federation, Saransk, the Republic of Mordovia
A. V. Kokorev
Obninsk Institute for Nuclear Power Engineering of the National Research Nuclear University MEPhI (Moscow Engineering Physics Institute)
Email: azabor@mail.ru
Russian Federation, Obninsk
K. G. Gurevich
A. I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia
Email: azabor@mail.ru
Russian Federation, Moscow
L. A. Tatarina
A. I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia
Email: azabor@mail.ru
Russian Federation, Moscow
D. V. Yunina
A. I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of Russia
Email: azabor@mail.ru
Russian Federation, Moscow
