Dynamics of the Pro-Oxidant/Antioxidant System Parameters in Wound Discharge and Plasma in Experimental Purulent Wound during Its Technological Liquid Phase Treatment
- Authors: Bykov I.M.1, Basov A.A.1, Malyshko V.V.1, Dzhimak S.S.2, Fedosov S.R.2, Moiseev A.V.3
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Affiliations:
- Kuban State Medical University, the Ministry of Health of the Russian Federation
- Kuban State University
- Kuban State Agrarian University
- Issue: Vol 163, No 2 (2017)
- Pages: 268-271
- Section: Experimental Methods for Clinical Practice
- URL: https://journals.rcsi.science/0007-4888/article/view/238809
- DOI: https://doi.org/10.1007/s10517-017-3781-3
- ID: 238809
Cite item
Abstract
The dynamics of the pro-oxidant/antioxidant system of rabbits was studied at the local (in exudate) and systemic (blood) levels during therapy of purulent wounds in liquid medium with the use of a programmed device and the efficiency of the proposed technological method was compared with that of classical methods for the treatment of these wounds. More rapid recovery of the indicators of the pro-oxidant/antioxidant system to physiological values in the postoperative period was observed after treatment by the proposed method (7 days vs. 10 days after standard treatment), these results attest to strengthening of the adaptation potential in laboratory animals. The intensity of free radical oxidation in the exudate decreased by 26.6% in animals treated by the technological method. These data indicated acceleration of the regenerative processes at the local level.
About the authors
I. M. Bykov
Kuban State Medical University, the Ministry of Health of the Russian Federation
Email: son_sunytch@mail.ru
Russian Federation, Krasnodar
A. A. Basov
Kuban State Medical University, the Ministry of Health of the Russian Federation
Author for correspondence.
Email: son_sunytch@mail.ru
Russian Federation, Krasnodar
V. V. Malyshko
Kuban State Medical University, the Ministry of Health of the Russian Federation
Email: son_sunytch@mail.ru
Russian Federation, Krasnodar
S. S. Dzhimak
Kuban State University
Email: son_sunytch@mail.ru
Russian Federation, Krasnodar
S. R. Fedosov
Kuban State University
Email: son_sunytch@mail.ru
Russian Federation, Krasnodar
A. V. Moiseev
Kuban State Agrarian University
Email: son_sunytch@mail.ru
Russian Federation, Krasnodar