Enzyme Immunoassay of Antibodies to Endogenous Bioregulators for Evaluating the Risk of Heart Disease
- Authors: Morozova V.S.1, Petrochenko S.N.1, Myagkova M.A.1, Bachurin S.O.1
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Affiliations:
- Institute of Physiologically Active Substances, Russian Academy of Sciences, Russia
- Issue: Vol 163, No 1 (2017)
- Pages: 65-67
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238651
- DOI: https://doi.org/10.1007/s10517-017-3739-5
- ID: 238651
Cite item
Abstract
The levels of natural antibodies to β-endorphin, bradykinin, histamine, dopamine, and serotonin were measured in 271 cardiological patients in order to evaluate the severity of their clinical status. The patients were distributed into groups differing by the course of the pathological process. The levels of natural antibodies to all antigens were maximum in patients with cardiosclerosis: the content of antibodies to β-endorphin surpassed the control by 46%, to histamine by 62%, to bradykinin by 36%, to dopamine by 49%, and to serotonin by 65%.
About the authors
V. S. Morozova
Institute of Physiologically Active Substances, Russian Academy of Sciences, Russia
Author for correspondence.
Email: vmorozova@gmail.com
Russian Federation, Chernogolovka, Moscow Region
S. N. Petrochenko
Institute of Physiologically Active Substances, Russian Academy of Sciences, Russia
Email: vmorozova@gmail.com
Russian Federation, Chernogolovka, Moscow Region
M. A. Myagkova
Institute of Physiologically Active Substances, Russian Academy of Sciences, Russia
Email: vmorozova@gmail.com
Russian Federation, Chernogolovka, Moscow Region
S. O. Bachurin
Institute of Physiologically Active Substances, Russian Academy of Sciences, Russia
Email: vmorozova@gmail.com
Russian Federation, Chernogolovka, Moscow Region