Age-Specific Dynamics of Corpus Callosum Development in Children and its Peculiarities in Infantile Cerebral Palsy
- Authors: Krasnoshchekova E.I.1, Zykin P.A.1, Tkachenko L.A.1, Aleksandrov T.A.1,2, Sereda V.M.1,2, Yalfimov A.N.2
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Affiliations:
- St. Petersburg State University
- St. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation
- Issue: Vol 161, No 6 (2016)
- Pages: 853-857
- Section: Methods
- URL: https://journals.rcsi.science/0007-4888/article/view/237853
- DOI: https://doi.org/10.1007/s10517-016-3528-6
- ID: 237853
Cite item
Abstract
The age dynamics of corpus callosum development was studied on magnetic resonance images of the brain in children aged 2-11 years without neurological abnormalities and with infantile cerebral palsy. The areas of the total corpus callosum and its segments are compared in the midsagittal images. Analysis is carried out with the use of an original formula: proportion of areas of the anterior (genu, CC2; and anterior part, CC3) and posterior (isthmus, CC6 and splenium, CC7) segments: kCC=(CC2+CC3)×CC6/CC7. The results characterize age-specific dynamics of the corpus callosum development and can be used for differentiation, with high confidence, of the brain of children without neurological abnormalities from the brain patients with infantile cerebral palsy.
About the authors
E. I. Krasnoshchekova
St. Petersburg State University
Author for correspondence.
Email: krasnelena@bio.spbu.ru
Russian Federation, St. Petersburg
P. A. Zykin
St. Petersburg State University
Email: krasnelena@bio.spbu.ru
Russian Federation, St. Petersburg
L. A. Tkachenko
St. Petersburg State University
Email: krasnelena@bio.spbu.ru
Russian Federation, St. Petersburg
T. A. Aleksandrov
St. Petersburg State University; St. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation
Email: krasnelena@bio.spbu.ru
Russian Federation, St. Petersburg; St. Petersburg
V. M. Sereda
St. Petersburg State University; St. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation
Email: krasnelena@bio.spbu.ru
Russian Federation, St. Petersburg; St. Petersburg
A. N. Yalfimov
St. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation
Email: krasnelena@bio.spbu.ru
Russian Federation, St. Petersburg