Development and Differentiation of Mesenchymal Bone Marrow Cells in Porous Permeable Titanium Nickelide Implants In Vitro and In Vivo
- Authors: Kokorev O.V.1, Khodorenko V.N.1, Radkevich A.A.1, Dambaev G.T.1, Gunter V.E.1
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Affiliations:
- Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University
- Issue: Vol 161, No 4 (2016)
- Pages: 587-592
- Section: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/237606
- DOI: https://doi.org/10.1007/s10517-016-3465-4
- ID: 237606
Cite item
Abstract
We studied the structure of porous permeable titanium nickelide used as the scaffold. In vitro population of the porous scaffold with multipotent mesenchymal stem bone marrow cells on days 7, 14, 21, and 28 was analyzed by scanning electron microscopy. Stage-by-stage histogenesis of the tissues formed from the bone marrow cells in the titanium nickelide scaffold in vivo is described in detail. Using mesenchymal stem cells, we demonstrated that porous permeable titanium nickelide scaffolds are unique incubators for cell cultures applicable for tissue engineering.
About the authors
O. V. Kokorev
Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University
Author for correspondence.
Email: kokorevov@yandex.ru
Russian Federation, Tomsk
V. N. Khodorenko
Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University
Email: kokorevov@yandex.ru
Russian Federation, Tomsk
A. A. Radkevich
Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University
Email: kokorevov@yandex.ru
Russian Federation, Tomsk
G. Ts. Dambaev
Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University
Email: kokorevov@yandex.ru
Russian Federation, Tomsk
V. E. Gunter
Research Institute of Medical Shape-Memory Materials and Implants, Tomsk National Research State University
Email: kokorevov@yandex.ru
Russian Federation, Tomsk