Relationship between Morphofunctional Changes in Open Traumatic Brain Injury and the Severity of Brain Damage in Rats
- Authors: Shakova F.M.1,2, Barskov I.V.1,2, Gulyaev M.V.1,3, Prokhorenko S.V.1, Romanova G.A.1,2, Grechko A.V.1
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Affiliations:
- Hospital for Incurable Patients, Research Medical and Rehabilitation Center
- Institute of Pathology and Pathomorphology
- Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University
- Issue: Vol 161, No 3 (2016)
- Pages: 419-424
- Section: Morphology and Pathomorphology
- URL: https://journals.rcsi.science/0007-4888/article/view/237478
- DOI: https://doi.org/10.1007/s10517-016-3429-8
- ID: 237478
Cite item
Abstract
A correlation between the severity of morphofunctional disturbances and the volume of brain tissue injury determined by MRT was demonstrated on the model of open traumatic brain injury in rats. A relationship between the studied parameters (limb placing and beam walking tests and histological changes) and impact force (the height of load fell onto exposed brain surface) was revealed.
About the authors
F. M. Shakova
Hospital for Incurable Patients, Research Medical and Rehabilitation Center; Institute of Pathology and Pathomorphology
Author for correspondence.
Email: shakova.fatima@yandex.ru
Russian Federation, Moscow; Moscow
I. V. Barskov
Hospital for Incurable Patients, Research Medical and Rehabilitation Center; Institute of Pathology and Pathomorphology
Email: shakova.fatima@yandex.ru
Russian Federation, Moscow; Moscow
M. V. Gulyaev
Hospital for Incurable Patients, Research Medical and Rehabilitation Center; Faculty of Fundamental Medicine, M. V. Lomonosov Moscow State University
Email: shakova.fatima@yandex.ru
Russian Federation, Moscow; Moscow
S. V. Prokhorenko
Hospital for Incurable Patients, Research Medical and Rehabilitation Center
Email: shakova.fatima@yandex.ru
Russian Federation, Moscow
G. A. Romanova
Hospital for Incurable Patients, Research Medical and Rehabilitation Center; Institute of Pathology and Pathomorphology
Email: shakova.fatima@yandex.ru
Russian Federation, Moscow; Moscow
A. V. Grechko
Hospital for Incurable Patients, Research Medical and Rehabilitation Center
Email: shakova.fatima@yandex.ru
Russian Federation, Moscow