Cardiac Autonomic Drive during Arterial Hypertension and Metabolic Disturbances
- Authors: Kseneva S.I.1, Borodulina E.V.1, Trifonova O.Y.1, Udut V.V.2
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Affiliations:
- E.D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
- National Research Tomsk State University
- Issue: Vol 161, No 2 (2016)
- Pages: 237-240
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237296
- DOI: https://doi.org/10.1007/s10517-016-3385-3
- ID: 237296
Cite item
Abstract
ANS support of the cardiac work was assessed with analysis of heart rate variability in representative samples of patients with arterial hypertension and metabolic disturbances manifested by overweight, classes I-II obesity, compromised glucose tolerance, and type II diabetes. Initially enhanced sympathetic effects on the heart rate demonstrated no further increase during the orthostatic test in contrast to suprasegmentary influences enhanced by this test. The pronouncedness of revealed peculiarities in ANS drive to the heart correlated with metabolic disturbances, and these peculiarities attained maximum in patients with type II diabetes.
About the authors
S. I. Kseneva
E.D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Author for correspondence.
Email: viksbest@mail.ru
Russian Federation, Tomsk
E. V. Borodulina
E.D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: viksbest@mail.ru
Russian Federation, Tomsk
O. Yu. Trifonova
E.D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: viksbest@mail.ru
Russian Federation, Tomsk
V. V. Udut
National Research Tomsk State University
Email: viksbest@mail.ru
Russian Federation, Tomsk