Ultrastructure of Cardiomyocytes and Blood Capillary Endotheliocytes in the Myocardium under Conditions of Experimental Mechanical Injury to the Heart
- Authors: Novoselov V.P.1, Savchenko S.V.1, Porvin A.N.1, Koshlyak D.A.1, Nadev A.P.2, Ageeva T.A.2, Chikinev Y.V.3, Polyakevich A.S.3
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Affiliations:
- Department of Forensic Medicine, Novosibirsk State Medical University
- Department of Pathology, Novosibirsk State Medical University
- Department of Hospital and Pediatric Surgery, Novosibirsk State Medical University
- Issue: Vol 161, No 1 (2016)
- Pages: 134-136
- Section: Morphology and Pathomorphology
- URL: https://journals.rcsi.science/0007-4888/article/view/237202
- DOI: https://doi.org/10.1007/s10517-016-3363-9
- ID: 237202
Cite item
Abstract
We studied ultrastructural changes in cardiomyocytes and blood capillary endotheliocytes in the ventricular myocardium in response to mechanical injury of the heart of varying severity in Wistar rats. Acute alterative changes in cardiomyocyte and endotheliocyte ultrastructure indicate impairment of the energy-producing, contractile, and protein-synthesizing functions of the cells after mechanical injury. These disorders play the key role in the development of acute contractile insufficiency of the myocardium in mechanical injury to the heart.
About the authors
V. P. Novoselov
Department of Forensic Medicine, Novosibirsk State Medical University
Email: dr.serg62@yandex.ru
Russian Federation, Novosibirsk
S. V. Savchenko
Department of Forensic Medicine, Novosibirsk State Medical University
Author for correspondence.
Email: dr.serg62@yandex.ru
Russian Federation, Novosibirsk
A. N. Porvin
Department of Forensic Medicine, Novosibirsk State Medical University
Email: dr.serg62@yandex.ru
Russian Federation, Novosibirsk
D. A. Koshlyak
Department of Forensic Medicine, Novosibirsk State Medical University
Email: dr.serg62@yandex.ru
Russian Federation, Novosibirsk
A. P. Nadev
Department of Pathology, Novosibirsk State Medical University
Email: dr.serg62@yandex.ru
Russian Federation, Novosibirsk
T. A. Ageeva
Department of Pathology, Novosibirsk State Medical University
Email: dr.serg62@yandex.ru
Russian Federation, Novosibirsk
Yu. V. Chikinev
Department of Hospital and Pediatric Surgery, Novosibirsk State Medical University
Email: dr.serg62@yandex.ru
Russian Federation, Novosibirsk
A. S. Polyakevich
Department of Hospital and Pediatric Surgery, Novosibirsk State Medical University
Email: dr.serg62@yandex.ru
Russian Federation, Novosibirsk