Comparative Analysis of the Proliferative Potential of Human Mesenchymal Stromal Cells from Extraembryonic Organs, Endometrium, and Adipose Tissue
- Authors: Fedorova I.A.1, Rudimova Y.V.1, Yushina M.N.1, Chuprynin V.D.1, Savilova A.M.1
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Affiliations:
- V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
- Issue: Vol 160, No 4 (2016)
- Pages: 548-554
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236783
- DOI: https://doi.org/10.1007/s10517-016-3216-6
- ID: 236783
Cite item
Abstract
Proliferative activity of mesenchymal stromal cells isolated from five sources (chorionic villi, Wharton’s jelly, amnion, endometrium, and adipose tissue) was compared by flow cytometry and real-time PCR (by the content of mRNA of genes encoding of cell cycle regulators). Mesenchymal stromal cells derived from the endometrium demonstrated maximum stability and high proliferative potential.
About the authors
I. A. Fedorova
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Author for correspondence.
Email: irina.genet@gmail.com
Russian Federation, Moscow
Y. V. Rudimova
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: irina.genet@gmail.com
Russian Federation, Moscow
M. N. Yushina
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: irina.genet@gmail.com
Russian Federation, Moscow
V. D. Chuprynin
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: irina.genet@gmail.com
Russian Federation, Moscow
A. M. Savilova
V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: irina.genet@gmail.com
Russian Federation, Moscow