Assessment of Functional Disturbances in the Central Nervous System Caused by Severe Carbon Monoxide Poisoning in Rats
- Authors: Tolkach P.G.1, Basharin V.A.1, Grebenyuk A.N.1
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Affiliations:
- S. M. Kirov Military Medical Academy, Ministry of Defense of the Russian Federation
- Issue: Vol 160, No 4 (2016)
- Pages: 462-464
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236733
- DOI: https://doi.org/10.1007/s10517-016-3197-5
- ID: 236733
Cite item
Abstract
An experimental model was developed for assessment of disturbances in CNS functions of laboratory animals caused by severe carbon monoxide poisoning. Normalization of the state of experimental rats after acute poisoning was accompanied by the development of cognitive abnormalities. Disturbances in the long-term memory were observed on days 1 and 14 after CO poisoning, while abnormalities in the short-term memory developed on days 1, 7, and 14. Learning impairment were recorded on day 8, while the training course began on day 7.
About the authors
P. G. Tolkach
S. M. Kirov Military Medical Academy, Ministry of Defense of the Russian Federation
Author for correspondence.
Email: pusher6@yandex.ru
Russian Federation, St. Petersburg
V. A. Basharin
S. M. Kirov Military Medical Academy, Ministry of Defense of the Russian Federation
Email: pusher6@yandex.ru
Russian Federation, St. Petersburg
A. N. Grebenyuk
S. M. Kirov Military Medical Academy, Ministry of Defense of the Russian Federation
Email: pusher6@yandex.ru
Russian Federation, St. Petersburg