Stabilization of Homeostasis in Rats during Cold Exposure with Ethanol
- Authors: Kolosova O.N.1, Kershengolts B.M.1
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Affiliations:
- Institute of Biological Problems of Cryolithozone, Siberian Division of the Russian Academy of Sciences
- Issue: Vol 160, No 3 (2016)
- Pages: 300-303
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/236692
- DOI: https://doi.org/10.1007/s10517-016-3156-1
- ID: 236692
Cite item
Abstract
The role of ethanol metabolism system in adaptation of laboratory animals to cold temperatures was shown. Cold stress (1-2°C) modeled in male Wistar rats over 7 weeks significantly modulated endogenous ethanol metabolism and led to reorganization of many physiological systems, which resulted in activation of metabolic processes. Under these conditions, endogenous ethanol was utilized as the most easily and fast metabolized energy substrate, due to which its blood concentration decreased and was replenished at the expense of exogenous ethanol. Normalization of blood ethanol concentration led to better adaptation to cold.
About the authors
O. N. Kolosova
Institute of Biological Problems of Cryolithozone, Siberian Division of the Russian Academy of Sciences
Author for correspondence.
Email: kolosova.olga8@inbox.ru
Russian Federation, Yakutsk
B. M. Kershengolts
Institute of Biological Problems of Cryolithozone, Siberian Division of the Russian Academy of Sciences
Email: kolosova.olga8@inbox.ru
Russian Federation, Yakutsk