Inflammatory immune infiltration in human tumors: Role in pathogenesis and prognostic and diagnostic value
- 作者: Bogolyubova A.1,2, Belousov P.1,2
-
隶属关系:
- Engelhardt Institute of Molecular Biology
- Biological Faculty
- 期: 卷 81, 编号 11 (2016)
- 页面: 1261-1273
- 栏目: Review
- URL: https://journals.rcsi.science/0006-2979/article/view/151078
- DOI: https://doi.org/10.1134/S0006297916110043
- ID: 151078
如何引用文章
详细
The cellular microenvironment directly and indirectly influences tumor development and possesses prognostic and in some cases diagnostic value. Over the years, understanding of structural organization of the immune/inflammatory moiety of neoplasms as well as in-depth phenotypic and transcriptomic profiling of its cellular components together provide more and more insights in both basic and translational medical science. In this review, we will discuss the specific roles of various stromal cells and their impact on neoplastic progression as well as address the use of quantitative and phenotypic analysis of immune/inflammatory infiltrate for diagnostics and predicting the clinical course of human malignancies.
作者简介
A. Bogolyubova
Engelhardt Institute of Molecular Biology; Biological Faculty
编辑信件的主要联系方式.
Email: apollinariya.bogolyubova@gmail.com
俄罗斯联邦, Moscow, 119991; Moscow, 119991
P. Belousov
Engelhardt Institute of Molecular Biology; Biological Faculty
Email: apollinariya.bogolyubova@gmail.com
俄罗斯联邦, Moscow, 119991; Moscow, 119991
![](/img/style/loading.gif)