Bacterial toxin–antitoxin systems: Properties, functional significance, and possibility of use (Review)
- Авторы: Klimina K.M.1, Poluektova E.U.1, Danilenko V.N.1
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Учреждения:
- N.I. Vavilov Institute of General Genetics
- Выпуск: Том 53, № 5 (2017)
- Страницы: 494-505
- Раздел: Article
- URL: https://journals.rcsi.science/0003-6838/article/view/152286
- DOI: https://doi.org/10.1134/S0003683817050076
- ID: 152286
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Аннотация
Toxin–antitoxin systems are genetic modules usually consisting of two genes encoding a stable toxin and labile antidote (antitoxin). These systems are localized on plasmids, phages, and chromosomes and are widespread in bacteria and archaea. The review summarizes recent data regarding the classifications of toxin–antitoxin systems, their mechanisms of action and toxin targets, as well as their functional significance for bacterial cells and possibility of use.
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Об авторах
K. Klimina
N.I. Vavilov Institute of General Genetics
Автор, ответственный за переписку.
Email: ppp843@yandex.ru
Россия, Moscow, 119991
E. Poluektova
N.I. Vavilov Institute of General Genetics
Email: ppp843@yandex.ru
Россия, Moscow, 119991
V. Danilenko
N.I. Vavilov Institute of General Genetics
Email: ppp843@yandex.ru
Россия, Moscow, 119991
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